L
Ludovic J. Chassin
Researcher at University of Cambridge
Publications - 33
Citations - 3685
Ludovic J. Chassin is an academic researcher from University of Cambridge. The author has contributed to research in topics: Insulin & Artificial pancreas. The author has an hindex of 20, co-authored 33 publications receiving 3480 citations. Previous affiliations of Ludovic J. Chassin include City University London.
Papers
More filters
Journal ArticleDOI
Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes
Roman Hovorka,Valentina Canonico,Ludovic J. Chassin,Ulrich Haueter,Massimo Massi-Benedetti,Marco Orsini Federici,Thomas R. Pieber,Helga C. Schaller,Lukas Schaupp,Thomas Vering,Malgorzata E. Wilinska +10 more
TL;DR: Adapt nonlinear model predictive control is promising for the control of glucose concentration during fasting conditions in subjects with type 1 diabetes.
Journal ArticleDOI
Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial
Roman Hovorka,Janet M. Allen,Daniela Elleri,Ludovic J. Chassin,Julie Harris,Dongyuan Xing,Craig Kollman,Tomas Hovorka,Anne Mette F. Larsen,Marianna Nodale,Alessandra De Palma,Malgorzata E. Wilinska,Carlo L. Acerini,David B. Dunger +13 more
TL;DR: Whether closed-loop insulin delivery could control overnight blood glucose in young people with type 1 diabetes and reduce risk of nocturnal hypoglycaemia in children and adolescents with type 2 diabetes is established.
Journal ArticleDOI
Partitioning glucose distribution/transport, disposal, and endogenous production during IVGTT.
Roman Hovorka,Fariba Shojaee-Moradie,Paul V. Carroll,Ludovic J. Chassin,Ian J. Gowrie,Nicola Jackson,Romulus S. Tudor,A. Margot Umpleby,Richard H. Jones +8 more
TL;DR: It is concluded that, in healthy subjects during an IVGTT, the two peripheral insulin effects account jointly for approximately one-half of the overall insulin-stimulated glucose lowering, each effect contributing equally.
Journal ArticleDOI
Insulin kinetics in type-1 diabetes: continuous and bolus delivery of rapid acting insulin
Malgorzata E. Wilinska,Ludovic J. Chassin,Helga C. Schaller,Lukas Schaupp,Thomas R. Pieber,Roman Hovorka +5 more
TL;DR: Models representing the dependence of insulin absorption rate on insulin disappearance and the remote insulin effect on its volume of distribution could not be validated suggesting that these effects are not present or cannot be detected during physiological conditions.
Journal ArticleDOI
Simulation Environment to Evaluate Closed-Loop Insulin Delivery Systems in Type 1 Diabetes
Malgorzata E. Wilinska,Ludovic J. Chassin,Carlo L. Acerini,Janet M. Allen,David B. Dunger,Roman Hovorka +5 more
TL;DR: Close-loop trials in humans should be preceded and concurrently guided by highly efficient and resource-saving computer-based simulations, and validity of population-based predictions obtained with the simulation environment is demonstrated.