Luis M. Ruilope

TL;DR: This analysis of patients with and without OSA evaluated the blood pressure-lowering effect of sympathetic modulation by renal denervation (RDN) in a real-world setting, and found that RDN resulted in significant BP reductions at 6 months in hypertensive patients with a history of hypertension and regardless of continuous positive airway pressure usage in OSA patients.

TL;DR: The presence of proteinuria has been shown to be an excellent predictor for a worse outcome of renal function, and studies are needed in which the strict control of arterial hypertension combined with a decrease in proteinuria are considered.

TL;DR: Available data show that positive efficacy and a good tolerability profile of LCZ696 in the treatment of arterial hypertension as well as preliminary data indicate that it can also be useful in thereatment of cardiovascular disease.

TL;DR: More than one-third of the hypertensive population included in the Spanish ABPM Registry can be considered as SPRINT candidates, although one out of five have values of 24-hour SBP below 120 mm Hg, suggesting that knowledge of ABPM values could be helpful when planning a treatment intensification in high-risk patients.

TL;DR: It is concluded that in refractory hypertension fenoldopam has potent renal and systemic vasodilatory properties through which blood pressure falls and is also facilitated by its marked diuretic and natriuretic properties.