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Luis M. Ruilope

Researcher at European University of Madrid

Publications -  891
Citations -  109166

Luis M. Ruilope is an academic researcher from European University of Madrid. The author has contributed to research in topics: Blood pressure & Renal function. The author has an hindex of 94, co-authored 841 publications receiving 97778 citations. Previous affiliations of Luis M. Ruilope include Lund University & Mayo Clinic.

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Cardiorenal protection during chronic renin-angiotensin-aldosterone system suppression: evidences and caveats.

TL;DR: New horizons are opened to manage the RAAS blockade in the cardiorenal disease through using the positive combination of an ACEi or an ARB plus and aldosterone antagonist, renin inhibitors, or other forms of blockade using new members as LCZ696.
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Effects of angiotensin converting enzyme inhibitors on the progression of renal failure and proteinuria in humans.

TL;DR: Captopril slowed the progression of chronic renal failure and on the rate of urinary protein excretion and was able to reduce the proteinuria of non-diabetic glomerular origin.
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3d.02: blood pressure variability increases with advancing chronic kidney disease stage. a cross-sectional analysis of 14,382 hypertensive patients from spain.

TL;DR: Increased short-term BP variability was significantly associated with progressive CKD stages in a large sample of hypertensive patients, and this association was stronger for SBP than for DBP, and for nighttime than for daytime BP.
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Should diuretics always be included as initial antihypertensive management in early-stage CKD?

TL;DR: Extracellular volume expansion is an important, if not the most important, contributing factor to hypertension seen in chronic kidney disease and diuretics have been a useful tool to manage volume overload and to achieve strict blood pressure control in patients with Chronic kidney disease.