Luiz Antonio Mendonça Alves da Costa

Bio: Luiz Antonio Mendonça Alves da Costa is an academic researcher from Federal University of Roraima. The author has contributed to research in topics: Essential oil & Antimicrobial. The author has an hindex of 6, co-authored 13 publications receiving 243 citations. Previous affiliations of Luiz Antonio Mendonça Alves da Costa include Universidade Federal de Mato Grosso.

Color, phenolic and flavonoid content, and antioxidant activity of honey from Roraima, Brazil

Abstract: The total phenolic and flavonoid content, color, and antioxidant activity were evaluated from ten honey samples from Apis mellifera L. collected from Roraima State, Brazil. The total phenolic content was determined using the Folin-Ciocalteu reagent and ranged from 250 to 548 mg gallic acid kg –1 of honey. The total flavonoid content was obtained using two methods: total flavones/flavonols were determined with aluminum chloride, and flavonones/dihydroflavonols were determined with 2,4-dinitrophenylhydrazine. The results ranged from 9 to 48.6 mg of quercetine kg –1 of honey and 1805 to 2606 mg of pinocembrin kg –1 of honey, respectively. Antioxidant activity was measured with 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavengers, and the results of the IC 50 ranged from 3.17 to 8.79 mg/mL. Statistical analysis demonstrated positive correlations between color intensity, flavone and flavonol content, and phenolic content and negative correlations with antioxidant capacity.

Seasonal Variations in Lipid Content, Fatty Acid Composition and Nutritional Profiles of Five Freshwater Fish from the Amazon Basin

Abstract: Fish from the Amazon Basin are affected by oscillations in the river water volume, which influences the diet of animal species. This study was aimed at evaluating seasonal variations in lipid content, fatty acid composition and nutritional profiles of five fish species from the Amazon Basin. The lipid contents of all fish species were observed to be lower in flood periods than in drought periods; Brachyplatystoma flavicans showed the largest variation (6.75–15.43 %) between these periods, while Colossoma macropomum showed no significant difference (p > 0.05). The fatty acid composition in the five fish species varied throughout seasonal periods; saturated fatty acid (SFA) contents decreased in flood periods, whereas polyunsaturated fatty acid (PUFA) contents significantly (p < 0.05) increased for all the species in the same period. Leporinus friderici showed the highest content of α-linolenic acid, (LNA 14.86 mg g−1) and Colossoma macropomum presented the highest content of docosahexaenoic acid (DHA 26.13 mg g−1) in flood periods. Prochilodus nigricans showed the lowest content of arachidonic acid (AA) in both periods, while Brachyplatystoma flavicans showed the greatest amount of AA, 18.77 mg g−1 in drought period and 22.10 mg g−1 in flood period. All the fish species presented favorable indices of nutritional quality of lipid fraction, suggesting that consumption of these species could be considered beneficial to human health.

CHEMICAL COMPOSITIONS AND ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF PROPOLIS PRODUCED BY Frieseomelitta longipes AND Apis mellifera BEES

Abstract: Edineide Cristina A. de Souzaa, Etyene Janyne G. da Silvaa, Hayron Kalil C. Cordeirob, Nauara M. Lage Filhob, Felipe M. A. da Silvac, Diany Lucy S. dos Reisd, Carla Portod, Eduardo J. Pilaud, Luiz Antonio M. A. da Costaa, Afonso D. L. de Souzac, Cristiano Menezese and Adriana Flacha,*¤ Departamento de Química, Universidade Federal de Roraima, 69310-000, Boa Vista – RR, Brasil Universidade Federal Rural da Amazônia, 66075-110 Belém – PA, Brasil Departamento de Química, Universidade Federal da Amazônia, 69077-000, Manaus – AM, Brasil Departamento de Química, Universidade Estadual de Maringá, 87020-900, Maringá – PR, Brasil Embrapa Amazônia Oriental, 66095-903 Belém – PA, Brasil

Antimicrobial Activity of Some Essential Oils-Present Status and Future Perspectives.

Abstract: Extensive documentation on the antimicrobial properties of essential oils and their constituents has been carried out by several workers. Although the mechanism of action of a few essential oil components has been elucidated in many pioneering works in the past, detailed knowledge of most of the compounds and their mechanism of action is still lacking. This knowledge is particularly important for the determination of the effect of essential oils on different microorganisms, how they work in combination with other antimicrobial compounds, and their interaction with food matrix components. Also, recent studies have demonstrated that nanoparticles (NPs) functionalized with essential oils have significant antimicrobial potential against multidrug- resistant pathogens due to an increase in chemical stability and solubility, decreased rapid evaporation and minimized degradation of active essential oil components. The application of encapsulated essential oils also supports their controlled and sustained release, which enhances their bioavailability and efficacy against multidrug-resistant pathogens. In the recent years, due to increasingly negative consumer perceptions of synthetic preservatives, interest in essential oils and their application in food preservation has been amplified. Moreover, the development of resistance to different antimicrobial agents by bacteria, fungi, viruses, parasites, etc. is a great challenge to the medical field for treating the infections caused by them, and hence, there is a pressing need to look for new and novel antimicrobials. To overcome these problems, nano-encapsulation of essential oils and exploiting the synergies between essential oils, constituents of essential oils, and antibiotics along with essential oils have been recommended as an answer to this problem. However, less is known about the interactions that lead to additive, synergistic, or antagonistic effects. A contributing role of this knowledge could be the design of new and more potent antimicrobial blends, and understanding of the interplay between the components of crude essential oils. This review is written with the purpose of giving an overview of current knowledge about the antimicrobial properties of essential oils and their mechanisms of action, components of essential oils, nano-encapsulated essential oils, and synergistic combinations of essential oils so as to find research areas that can facilitate applications of essential oils to overcome the problem of multidrug-resistant micro-organisms.

Antimicrobial Properties of Plant Essential Oils against Human Pathogens and Their Mode of Action: An Updated Review.

Abstract: A wide range of medicinal and aromatic plants (MAPs) have been explored for their essential oils in the past few decades. Essential oils are complex volatile compounds, synthesized naturally in different plant parts during the process of secondary metabolism. Essential oils have great potential in the field of biomedicine as they effectively destroy several bacterial, fungal, and viral pathogens. The presence of different types of aldehydes, phenolics, terpenes, and other antimicrobial compounds means that the essential oils are effective against a diverse range of pathogens. The reactivity of essential oil depends upon the nature, composition, and orientation of its functional groups. The aim of this article is to review the antimicrobial potential of essential oils secreted from MAPs and their possible mechanisms of action against human pathogens. This comprehensive review will benefit researchers who wish to explore the potential of essential oils in the development of novel broad-spectrum key molecules against a broad range of drug-resistant pathogenic microbes.

The fish

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Anise (Pimpinella anisum L.), a dominant spice and traditional medicinal herb for both food and medicinal purposes

Abstract: Aromatic plants such as anise seed have a long traditional use in both folk and conventional medicine and of course in the pharmaceutical industry. Important compounds found in anise seed include e...