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Luoyi Bai

Bio: Luoyi Bai is an academic researcher from Central China Normal University. The author has contributed to research in topics: Fluorophore & Phosgene. The author has an hindex of 2, co-authored 2 publications receiving 55 citations.

Papers
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Journal ArticleDOI
TL;DR: In this article, an ultrasensitive fluorescent turn-on probe (HBT-Phos) for rapid detection of the highly toxic phosgene is reported, which uses 2-(2′-hydroxyphenyl)benzothiazole(HBT), a well-known excited-state intramolecular proton transfer (ESIPT) dye as the fluorophore and an oxime moiety as the reaction site.

53 citations

Journal ArticleDOI
TL;DR: In this article, a new colorimetric and ratiometric fluorescent probe was developed for rapid detection of palladium in aqueous solution under mild conditions, which is based on a novel phthalimide-rhodol dyad.
Abstract: In this paper, a new colorimetric and ratiometric fluorescent probe was developed for rapid detection of palladium in aqueous solution under mild conditions. This probe is based on a novel phthalimide-rhodol dyad, which has a unique ESIPT-FRET mechanism to give the desired ratiometric fluorescent signal changes. Optical sensing studies showed that this probe not only has high selectivity and sensitivity for palladium with a low detection limit of 31 nM, but also exhibits rapid and distinct colorimetric and ratiometric fluorescent signal changes with a large pseudo Stokes shift. In addition, the probe was successfully used for fluorescent imaging of palladium in living cells. Overall, this work provided a new ESIPT-FRET platform for development of ratiometric probes and a new attractive colorimetric and ratiometric fluorescent probe for detection of palladium.

32 citations


Cited by
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Journal ArticleDOI
TL;DR: In this review, recent advances made in the development and biological applications of synthetic ratiometric fluorescent probes are described and particular emphasis is given to organic dye-based ratiomet fluorescent probes that are designed to detect biologically important and relevant ions in cells and living organisms.
Abstract: Metal cations and anions are essential for versatile physiological processes. Dysregulation of specific ion levels in living organisms is known to have an adverse effect on normal biological events. Owing to the pathophysiological significance of ions, sensitive and selective methods to detect these species in biological systems are in high demand. Because they can be used in methods for precise and quantitative analysis of ions, organic dye-based ratiometric fluorescent probes have been extensively explored in recent years. In this review, recent advances (2015-2019) made in the development and biological applications of synthetic ratiometric fluorescent probes are described. Particular emphasis is given to organic dye-based ratiometric fluorescent probes that are designed to detect biologically important and relevant ions in cells and living organisms. Also, the fundamental principles associated with the design of ratiometric fluorescent probes and perspectives about how to expand their biological applications are discussed.

510 citations

Journal ArticleDOI
TL;DR: A readily available fluorescent probe based on an excited-state intramolecular proton transfer (ESIPT) dye phthalimide can be used for rapid, highly selective and sensitive detection of CORM-3 with a distinct turn-on green fluorescence change in aqueous solution, living cells and animals.
Abstract: CO-releasing molecule-3 (CORM-3) has been widely used recently as a convenient and safe CO donor to release exogenous CO in living cells and to study the effects of CO on cellular systems. Accordingly, development of effective methods for detecting and tracking CORM-3 in living systems is of great significance. In this work, a readily available fluorescent probe for detection of CORM-3 was reported for the first time. This probe is based on an excited-state intramolecular proton transfer (ESIPT) dye phthalimide and uses the reducing ability of CORM-3 to convert a nitro group to an amino group, and more importantly, it can be used for rapid, highly selective, and sensitive detection of CORM-3 with a distinct turn-on green fluorescence change in aqueous solution, living cells, and animals, thus providing a useful tool for studying CORM-3 in living systems.

58 citations

Journal ArticleDOI
TL;DR: A comprehensive review of the recent development and applications of excited-state intramolecular proton transfer-based (ESIPT-based) aggregation-induced emission luminogens (AIEgens) can be found in this paper .
Abstract: In this review, we present a systematic and comprehensive summary of the recent development and applications of excited‐state intramolecular proton transfer‐based (ESIPT‐based) aggregation‐induced emission luminogens (AIEgens), a type of promising materials that inherit the advantages of ESIPT and AIE, such as large Stokes shift, excellent photostability, and low self‐quenching. We first summarize the backbones that have been used to construct the ESIPT‐based AIEgens and classify the constructed ones based on the relation between ESIPT and AIE unit. According to the sensing mechanisms and design strategies, we have reviewed the applications of ESIPT‐based AIEgens in bioimaging, drug delivery systems, organic light‐emitting diodes, photo‐patterning, liquid crystal, and the detection of metal cations, anions, small molecules, biothiols, biological enzymes, latent fingerprinting, and so on. We have also reviewed the recent advances in the development of new theoretical methods for investigating molecular photochemistry in crystals and their applications in ESIPT‐based AIEgens. We discussed the remaining challenges in this field and the issues that need to be addressed. We anticipate that this review can provide a comprehensive picture of the current condition of research in this field, and promote researchers to make more efforts to develop novel ESIPT‐based AIEgens with new applications.

55 citations

Journal ArticleDOI
TL;DR: A novel fluorescent chemosensor, Phos-4, has been constructed with 1,8-naphthalimide as the fluorophore and 2-(2-aminophenyl)imidazol as the recognition sites for discrimination between phosgene and triphosgenes in a dual-channel mode for the first time.
Abstract: As highly toxic and accessible chemical reagents, phosgene and triphosgene have become a serious threat to public safety. So, it is highly desirable to develop facile methods to detect and recognize them. In this article, a novel fluorescent chemosensor, Phos-4, has been constructed with 1,8-naphthalimide as the fluorophore and 2-(2-aminophenyl)imidazol as the recognition sites for discrimination between phosgene and triphosgene in a dual-channel mode for the first time. Owing to the difference in electrophilicity between chlorocarbonyl and trichloromethoxycarbonyl, the sensing reaction of Phos-4 with phosgene undergoes two carbamylations to afford a cyclic product with green fluorescence, and only one carbamylation occurs for triphosgene to form a noncyclic product with blue fluorescence. The sensor Phos-4 exhibits high sensitivity (the limit of detection, 3.2 nM, for phosgene, and 1.9 nM, for triphosgene) and high selectivity in solutions. Furthermore, facile test papers containing Phos-4-embedded nanofibrous membrane have been fabricated by the electrospinning technology. The test papers can provide visual and selective detection of phosgene with a lower limit of detection (42 ppb) and a faster response (≤10 s) in the gas phase over those in solutions. The test paper with Phos-4 is promising to be a practical detection tool of gaseous phosgene.

42 citations

Journal ArticleDOI
TL;DR: A chemosensor containing an o-hydroxyaniline unit as the reaction site was developed for colorimetric and fluorimetric detection of phosgene, which showed fast response, high specificity, and an extremely low detection limit.

41 citations