L
Lutz Gissmann
Researcher at German Cancer Research Center
Publications - 207
Citations - 17618
Lutz Gissmann is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Cervical cancer & Virus. The author has an hindex of 66, co-authored 206 publications receiving 17106 citations.
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Journal ArticleDOI
Structure and transcription of human papillomavirus sequences in cervical carcinoma cells
Elisabeth Schwarz,U K Freese,Lutz Gissmann,Wolfgang Mayer,Birgit Roggenbuck,Armin Stremlau,Harald zur Hausen +6 more
TL;DR: It is found that the HPV 18 DNA is integrated into the cellular genome and is amplified in HeLa and 756 cells, and some of the transcripts are composed of HPV 18 and cellular sequences.
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Chapter 1: HPV in the etiology of human cancer.
TL;DR: The causal role of human papillomavirus in all cancers of the uterine cervix has been firmly established biologically and epidemiologically and co-infection with Chlamydia trachomatis and herpes simplex virus type-2 have been identified as established cofactors.
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Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers
TL;DR: The data support a genital origin of laryngeal papillomavirus infections and a possible role of this or related papillmavirus types in the induction of malignant genital tumors remains to be elucidated.
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Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles.
Reinhard Kirnbauer,Janet Taub,Heather Greenstone,Richard B.S. Roden,Matthias Dürst,Lutz Gissmann,D R Lowy,John T. Schiller +7 more
TL;DR: The ability to generate preparative amounts of HPV16 L1 and L1-L2 VLP may have implications for the development of a serological assay to detect anti-HPV16 virion immune responses to conformational epitopes and for immunoprophylaxis against HPV16 infection.
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Bead-based multiplex genotyping of human papillomaviruses
Markus Schmitt,Ignacio G. Bravo,Peter J.F. Snijders,Lutz Gissmann,Michael Pawlita,Tim Waterboer +5 more
TL;DR: Multiplex human papillomavirus genotyping (MPG), a quantitative and sensitive high-throughput procedure for the identification of multiple high- and low-risk genital HPV genotypes in a single reaction appears to be highly suitable for large-scale epidemiological studies and vaccination trials as well as for routine diagnostic purposes.