Author
M. Anthony McKervey
Other affiliations: University College Cork
Bio: M. Anthony McKervey is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: Calixarene & Enantioselective synthesis. The author has an hindex of 42, co-authored 150 publications receiving 8627 citations. Previous affiliations of M. Anthony McKervey include University College Cork.
Papers published on a yearly basis
Papers
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1,214 citations
Book•
19 Jan 1998
TL;DR: Synthesis of Alpha-Diazocarbonyl Compounds Catalysts for Metal Carbene Transformations Insertion Reactions Intermolecular Cyclopropanation and Related Addition Reactions Intramolecular cyclopropaneation and related addition Reactions Cycloaddition and Substitution Reactions with Aromatic and Heteroaromatic Compounds Generation and Reactions of Ylides from DBCs X-H InsertionReactions of DBC compounds (X = N,O,S,Se,P, Halogen) The
Abstract: Synthesis of Alpha-Diazocarbonyl Compounds Catalysts for Metal Carbene Transformations Insertion Reactions Intermolecular Cyclopropanation and Related Addition Reactions Intramolecular Cyclopropanation and Related Addition Reactions Cycloaddition and Substitution Reactions with Aromatic and Heteroaromatic Compounds Generation and Reactions of Ylides from Diazocarbonyl Compounds X-H Insertion Reactions of Diazocarbonyl Compounds (X = N,O,S,Se,P, Halogen) The Wolff Rearrangement and Related Reactions Reactions of Alpha-Diazocarbonyl Compounds with Aldehydes and Ketones Acid-Promoted Cyclization of Unsaturated and Aromatic Diazo Ketones Miscellaneous Diazocarbonyl Reactions Index
1,112 citations
TL;DR: This work aims to demonstrate the efforts towards in-situ applicability of EMMARM, which aims to provide real-time information about the physical properties of EMTs and their applications in the context of drug discovery and development.
Abstract: Alan Ford,† Hugues Miel, Aoife Ring,† Catherine N. Slattery,† Anita R. Maguire,*,†,‡ and M. Anthony McKervey* †Department of Chemistry and ‡School of Pharmacy, Analytical and Biological Chemistry Research Facility, Synthesis and Solid State Pharmaceutical Centre, University College Cork, Cork, Ireland Almac Discovery Ltd., David Keir Building, Stranmillis Road, Belfast BT9 5AG, United Kingdom Almac Sciences Ltd., Almac House, 20 Seagoe Industrial Estate, Craigavon BT63 5QD, United Kingdom
1,051 citations
15 Sep 1998
TL;DR: The Wolff Rearrangement and Related Reactions of Alpha-Diazocarbonyl Compounds with Aldehydes and Ketones are discussed in this paper, as well as other Diazocaronyl reactions.
Abstract: Synthesis of Alpha-Diazocarbonyl Compounds. Catalysts for Metal Carbene Transformations. Insertion Reactions. Intermolecular Cyclopropanation and Related Addition Reactions. Intramolecular Cyclopropanation and Related Addition Reactions. Cycloaddition and Substitution Reactions with Aromatic and Heteroaromatic Compounds. Generation and Reactions of Ylides from Diazocarbonyl Compounds. X-H Insertion Reactions of Diazocarbonyl Compounds (X = N,O,S,Se,P, Halogen). The Wolff Rearrangement and Related Reactions. Reactions of Alpha-Diazocarbonyl Compounds with Aldehydes and Ketones. Acid-Promoted Cyclization of Unsaturated and Aromatic Diazo Ketones. Miscellaneous Diazocarbonyl Reactions. Index.
628 citations
TL;DR: Des calix[n]arenes (n = 4, 6, 8) portant des cetoesters sont etudies; pour n=4, ils presentent a l'etat solide une conformation en cone, leurs cryptates avec des metaux alcalins sont egalement etude dans le but d'evaluer leurs proprietes ionophores as mentioned in this paper.
Abstract: Des calix[n]arenes (n=4, 6, 8) portant des cetoesters sont etudies; pour n=4, ils presentent a l'etat solide une conformation en cone, leurs cryptates avec des metaux alcalins sont egalement etudies dans le but d'evaluer leurs proprietes ionophores
543 citations
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10,370 citations
6,396 citations
TL;DR: The palladium-catalyzed cross-coupling reaction between organoboron compounds and organic halides or triflates provides a powerful and general methodology for the formation of carbon-carbon bonds as discussed by the authors.
2,712 citations
TL;DR: This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.
Abstract: The direct functionalization of C-H bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon-carbon and carbon-heteroatom bonds. This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.
2,391 citations
TL;DR: Several facets of these kinds of C–H functionalization reactions are discussed and a perspective on how this methodology has affected the synthesis of complex natural products and potential pharmaceutical agents are provided.
Abstract: Novel reactions that can selectively functionalize carbon-hydrogen bonds are of intense interest to the chemical community because they offer new strategic approaches for synthesis. A very promising 'carbon-hydrogen functionalization' method involves the insertion of metal carbenes and nitrenes into C-H bonds. This area has experienced considerable growth in the past decade, particularly in the area of enantioselective intermolecular reactions. Here we discuss several facets of these kinds of C-H functionalization reactions and provide a perspective on how this methodology has affected the synthesis of complex natural products and potential pharmaceutical agents.
1,843 citations