M.C. Woods

Bio: M.C. Woods is an academic researcher from Tohoku University. The author has contributed to research in topics: Ginkgolides & NMR spectra database. The author has an hindex of 12, co-authored 21 publications receiving 391 citations.

Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis

Abstract: The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the involvement of electronically excited states, generated upon absorption of photons. This produces transient reactive intermediates and significantly alters the reactivity of a chemical compound. The input of energy provided by light thus offers a means to produce strained and unique target compounds that cannot be assembled using thermal protocols. This review aims at highlighting photochemical transformations as a tool for rapidly accessing structurally and stereochemically diverse scaffolds. Synthetic designs based on photochemical transformations have the potential to afford complex polycyclic carbon skeletons with impressive efficiency, which are of high value in total synthesis.