M
M.Donald Whorton
Researcher at University of California, Berkeley
Publications - 2
Citations - 579
M.Donald Whorton is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Sperm & Sperm motility. The author has an hindex of 2, co-authored 2 publications receiving 563 citations.
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Journal ArticleDOI
An evaluation of the mouse sperm morphology test and other sperm tests in nonhuman mammals: A report of the U.S. environmental protection agency Gene-Tox program
Andrew J. Wyrobek,Laurie Gordon,James G. Burkhart,Mary W. Francis,Robert W. Kapp,Gideon Letz,Heinrich V. Malling,John C. Topham,M.Donald Whorton +8 more
TL;DR: The mouse sperm morphology test has potential use for identifying chemicals that induce spermatogenic dysfunction and perhaps heritable mutations, and is found to be highly sensitive to germ-cell mutagens.
Journal ArticleDOI
An evaluation of human sperm as indicators of chemically induced alterations of spermatogenic function. A report of the U.S. Environmental Protection Agency Gene-Tox Program.
Andrew J. Wyrobek,Laurie Gordon,James G. Burkhart,Mary W. Francis,Robert W. Kapp,Gideon Letz,Heinrich V. Malling,John C. Topham,M.Donald Whorton +8 more
TL;DR: There is strong evidence that human sperm tests can be used to identify chemicals that affect sperm production, but because of the limited understanding of underlying mechanisms, the extent to which they can detect mutagens, carcinogens or agents that affect fertility remains uncertain.