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M. Fátima das G. F. da Silva

Bio: M. Fátima das G. F. da Silva is an academic researcher from Federal University of São Carlos. The author has contributed to research in topics: Limonoid & Atta sexdens. The author has an hindex of 26, co-authored 94 publications receiving 1866 citations. Previous affiliations of M. Fátima das G. F. da Silva include Universidade Estadual de Londrina.


Papers
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Journal ArticleDOI
TL;DR: Results show that Toona has a less pronounced relationship to the Swietenioideae, and the known limonoids cedrelone and toonacilin and the sterols sitosterol, stigmasterol, campesterol and 3β-O-β- d -glucopyranosylsitosterol are characterised.

36 citations

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TL;DR: A phytochemical investigation of the stems of the South Brazilian endemic species Raulinoa echinata has led to the isolation of two new methoxylated protolimonoid epimers together with the known melianone and melianodiol.
Abstract: A phytochemical investigation of the stems of the South Brazilian endemic species Raulinoa echinata has led to the isolation of two new methoxylated protolimonoid epimers (1 and 2) together with the known melianone and melianodiol. The leaves afforded three glabretal-type triterpene derivatives esterified by N-methylanthranilic acid (3−5). Compounds 1 and 2 displayed weak inhibitory activity when assayed in vitro against trypomastigote forms of Trypanosoma cruzi. Compounds 1−5 were inactive in a brine shrimp (Artemia salina) lethality test.

36 citations

Journal ArticleDOI
TL;DR: The stems of Khaya senegalensis yielded three limonoids which appear to be novel and represent a novel group of methyl tricyclomeliac-7-oates.

35 citations

Journal ArticleDOI
TL;DR: The ability of T. arnobia males and females to detect volatile essential oils of seven Eucalyptus species was investigated and coupled gas chromatography-electroantennographic detection (GC-EAD) results suggest that this species uses several volatile cues to find its host.
Abstract: Eucalyptus is frequently attacked by the Brazilian eucalyptus brown looper, Thyrinteina arnobia. This caterpillar is regarded as the main lepidopterous pest of Eucalyptus and yet no practical and environmentally acceptable method of control currently exists. Electroantennographic techniques (EAG) have never before been used to detect semiochemicals that affect the behavior of T. arnobia. Thus, in this work, the ability of T. arnobia males and females to detect volatile essential oils of seven Eucalyptus species was investigated by EAG. We demonstrated that T. arnobia antennal olfactory system clearly showed differential sensitivity to several compounds, by coupled gas chromatography-electroantennographic detection (GC-EAD). Twenty-eight compounds were identified that elicited responses in T. arnobia, indicating that GC-EAD analysis may well be a useful means of screening active plant extracts for compounds that contribute to the observed behavior of this defoliator. The results also suggest that this species uses several volatile cues to find its host.

33 citations

Journal ArticleDOI
TL;DR: From the seeds of Toona ciliata, besides toonacilin, two novel limonoids: 12-deacetoxytoonaciliin and 6α-acetoxy-14β,15β-epoxyazadirone were isolated as discussed by the authors.

31 citations


Cited by
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Journal ArticleDOI
TL;DR: This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant, microbial and animal sources.

1,687 citations

Journal ArticleDOI
TL;DR: A historical introduction of drugs assayed against Chagas disease beginning in 1912 with the works of Mayer and Rocha Lima up to the experimental use of nitrofurazone, and a survey about new classes of synthetic and natural compounds studied after 1992/1993.
Abstract: In this "Critical Review" we made a historical introduction of drugs assayed against Chagas disease beginning in 1912 with the works of Mayer and Rocha Lima up to the experimental use of nitrofurazone. In the beginning of the 70s, nifurtimox and benznidazole were introduced for clinical treatment, but results showed a great variability and there is still a controversy about their use for chronic cases. After the introduction of these nitroheterocycles only a few compounds were assayed in chagasic patients. The great advances in vector control in the South Cone countries, and the demonstration of parasite in chronic patients indicated the urgency to discuss the etiologic treatment during this phase, reinforcing the need to find drugs with more efficacy and less toxicity. We also review potential targets in the parasite and present a survey about new classes of synthetic and natural compounds studied after 1992/1993, with which we intend to give to the reader a general view about experimental studies in the area of the chemotherapy of Chagas disease, complementing the previous papers of Brener (1979) and De Castro (1993).

822 citations

Journal ArticleDOI
TL;DR: Thome, Robert F. as mentioned in this paper presented the latest revision of the classification of the Class Angiospermae and replaces my 1983 and more recent 1992 synopses. And a new phyletic "shrub" replaces earlier versions, and attempts to indicate visually relative sizes and relationships among the superorders, orders, and suborders.
Abstract: Thome, Robert F. (Rancho Santa Ana Botanic Garden, Claremont, CA 91711). Classification and geography of the flowering plants. Bot. Rev.58(3): 225–348. 1992.—This treatment of the flowering plants is the latest revision of my classification of the Class Angiospermae and replaces my 1983 and more recent 1992 synopses. An update is necessary because so much new information has been published in the last decade pertinent to the classification of the flowering plants. About 870 such recent books, monographs, and other botanical papers are cited in the Introduction, listed primarily by the botanical discipline that they represent. Also considerable changes in my classification have been necessitated by my narrowed family- and ordinal-gap concepts, acceptance of the ending “-anae” for superorders in place of the traditional but inappropriate “-iflorae,” and acceptance of more prior or more widely used names for the categories above the family. A new phyletic “shrub” replaces earlier versions, and attempts to indicate visually relative sizes and relationships among the superorders, orders, and suborders. One table includes a statistical summary of floweringplant taxa: ca. 233,900 species of 12,650 genera, 437 families, and 708 subfamilies and undivided families in 28 superorders, 71 orders, and 71 suborders of Angiospermae. Three other tables summarize the known indigenous distribution of the families and subfamilies of angiosperms about the world. The synopsis lists the flowering plant taxa from the class down to the subfamily (and in Asteraceae down to the tribe) with indication of the degree of confidence I place in the circumscription and placement of each category above the subfamily, the best available estimates of the number of genera and species for each category, and the known indigenous distribution of each subfamily and family. Table V lists alphabetically the geographical abbreviations used in the synopsis. The extensive bibliography of recent literature should be helpful to those persons interested in the classification of the flowering plants.

518 citations