M
M. James Phillips
Researcher at University of Toronto
Publications - 66
Citations - 8306
M. James Phillips is an academic researcher from University of Toronto. The author has contributed to research in topics: FGL2 & Cholestasis. The author has an hindex of 34, co-authored 66 publications receiving 7776 citations. Previous affiliations of M. James Phillips include Université de Montréal & University Health Network.
Papers
More filters
Journal ArticleDOI
Histological grading and staging of chronic hepatitis.
Kamal G. Ishak,Amelia Baptista,Leonardo Bianchi,Francesco Callea,Jan De Groote,Fred Gudat,Helmut Denk,Valeer Desmet,Gerhard Korb,R. N. M. Macsween,M. James Phillips,Bernard G. Portmann,H. Poulsen,Peter J. Scheuer,Martin Schmid,Heribert Thaler +15 more
TL;DR: This research presents a meta-analysis of Anatomia e Istologia Patologica, a large quantity of which has never before been published in a peer-reviewed journal, which aims to provide real-time information about the immune system’s response to disease.
Journal ArticleDOI
Genetic modifiers of liver disease in cystic fibrosis.
Jaclyn R. Bartlett,Kenneth J. Friedman,Simon C. Ling,Rhonda G. Pace,Scott C. Bell,Billy Bourke,Giuseppe Castaldo,Carlo Castellani,Marco Cipolli,Carla Colombo,John L. Colombo,Dominique Debray,Adriana Fernandez,F. Lacaille,Milan Macek,Marion Rowland,Marion Rowland,Francesco Salvatore,Christopher J. Taylor,Claire E. Wainwright,Michael Wilschanski,Dana Zemkova,William B. Hannah,M. James Phillips,Mary Corey,Julian Zielenski,Ruslan Dorfman,Yunfei Wang,Fei Zou,Lawrence M. Silverman,Mitchell L. Drumm,Fred A. Wright,Ethan M. Lange,Peter R. Durie,Michael R. Knowles +34 more
TL;DR: The SERPINA1 Z allele is a risk factor for liver disease in CF and patients who carry the Z allele are at greater risk of developing severe liver disease with portal hypertension.
Journal ArticleDOI
The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis.
Philip A. Marsden,Qin Ning,L. S. Fung,Xioping Luo,Yue Chen,Michael Mendicino,Anand Ghanekar,Jeremy A. Scott,Teresa Miller,Camie W. Y. Chan,Mathew W.C. Chan,Wei He,Reginald M. Gorczynski,David R. Grant,David A. Clark,M. James Phillips,Gary A. Levy +16 more
TL;DR: Data indicate a critical role for Fgl2/fibroleukin in the pathophysiology of experimental and human viral hepatitis.
Journal ArticleDOI
Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine model.
TL;DR: It is shown, for the first time, that long-lived C578L/6J Cftr(-/-) mice develop manifestations of cystic fibrosis-like disease in all pathologically affected organs in the human form of cysts fibrosis.
Journal ArticleDOI
Murine hepatitis virus strain 1 produces a clinically relevant model of severe acute respiratory syndrome in A/J mice
Nadine De Albuquerque,Ehtesham Baig,Xue-Zhong Ma,Jianhua Zhang,William He,Andrea Rowe,Marlena V. Habal,Mingfeng Liu,Itay Shalev,Gregory P. Downey,Reginald M. Gorczynski,Jagdish Butany,Julian L. Leibowitz,Susan R. Weiss,Ian D. McGilvray,M. James Phillips,Eleanor N. Fish,Gary A. Levy +17 more
TL;DR: A potentially useful small animal model of human SARS is described, its pathogenesis is defined, and treatment strategies are suggested.