M M Prokofjeva

TL;DR: It is shown that AML cells transduced with short hairpin RNA vector targeting AE mRNAs have a dramatic decrease in growth rate that is caused by induction of apoptosis and deregulation of the cell cycle.

TL;DR: All natural fucoidans can be considered as potential anti-HIV agents regardless of their carbohydrate backbone and degree of sulfating, since their activity is shown at low concentrations.

TL;DR: It is shown that translation of a leaderless reporter mRNA is resistant to conditions when eIF2 and eIF4F, two key eukaryotic translation initiation factors, are inactivated in mammalian cells using the Fleeting mRNA Transfection technique (FLERT).

TL;DR: A straightforward screening approach for simultaneously evaluating the sensitivity of multiple HIV gag-pol mutants to antiviral drugs in one assay based on multi-colour lentiviral self-inactivating LeGO vector technology, providing a valuable new approach for the identification of novel anti-HIV drugs.

TL;DR: Significant and consistent changes in the abundance of five lincRNAs were found upon treatment of both colon cancer cell lines with all three chemotherapeutic drugs and the most frequent changes were detected for LINC00973.