Author
M. Rogge
Bio: M. Rogge is an academic researcher from University of Mainz. The author has contributed to research in topics: Aryne & Wittig reaction. The author has an hindex of 6, co-authored 12 publications receiving 100 citations.
Topics: Aryne, Wittig reaction, Carbazole, Sodium hydride, Enol
Papers
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46 citations
TL;DR: The cycloadducts3,5, and7, readily available from methoxy-substituted 3-vinylindoles1 and2, were dehydrogenated withDDQ to the coplanar [a]-anellated carbazoles4,6, and8 as discussed by the authors.
Abstract: The cycloadducts3,5, and7, readily available from methoxy-substituted 3-vinylindoles1 and2, were dehydrogenated withDDQ to the coplanar [a]-anellated carbazoles4,6, and8. Compound4a, also characterized by X-ray structural analysis, shows significant cytotoxicity against K562 und RXF393 human tumor cell lines.
14 citations
TL;DR: In this paper, the first chiral 3-and 2-vinylindoles bearing sulfoxide or (-)-menthyloxy functional groups at the β-vyl positions were synthesized by using the Horner-Wadsworth-Emmons and Wittig reactions.
12 citations
TL;DR: In this paper, an X-ray crystal structure analysis yields valuable information on constitutions and configurations in the biaryl series and the phenomenon of atropisomerism is discussed for this compound.
11 citations
9 citations
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1,143 citations
269 citations
TL;DR: This work presents the development of an unprecedented catalytic asymmetric Diels–Alder reaction of 3-vinylindoles 1 with different representative dienophiles 2 (Scheme 1).
Abstract: Diels–Alder type reactions are amongst the most useful transformations in organic chemistry for the construction of cyclohexene structures, often containing multiple stereocenters. Catalytic asymmetric variants of these [4+2] cycloadditions have been reported for different diene–dienophile combinations, showing in several instances outstanding synthetic utility. Herein, we present the development of an unprecedented catalytic asymmetric Diels–Alder reaction of 3-vinylindoles 1 with different representative dienophiles 2 (Scheme 1). Our studies were motivated by the stunning
199 citations
TL;DR: In this article, the potential utility of azodicarboxylates in various carbon-nitrogen bond-forming reactions is summarized, including electrophilic amination and pericyclic reactions.
Abstract: Azodicarboxylates have found applications in electrophilic amination reactions and in pericyclic reactions. The nucleophilic trigger in Mitsunobu reactions, that is, the zwitterion formed from triphenylphosphine and dialkyl azodicarboxylate, has been utilized recently in various heterocyclic constructions. This Focus Review summarizes the potential utility of azodicarboxylates in various carbon-nitrogen bond-forming reactions.
107 citations
103 citations