M
Maarten L. Simoons
Researcher at Cleveland Clinic
Publications - 9
Citations - 3720
Maarten L. Simoons is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: Myocardial infarction & Thrombolysis. The author has an hindex of 4, co-authored 9 publications receiving 3557 citations.
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An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction.
Maarten L. Simoons,Eric J. Topol,Robert M. Califf,Frans Van de Werf,Paul W. Armstrong,Philip Edmund Aylward,G.I. Barbash,Eric R. Bates,A. Betriu,James Chesebro,J Col,David de Bono,JM Gore,Alan Guerci,John R. Hampton +14 more
TL;DR: The findings of this large-scale trial indicate that accelerated t-PA given with intravenous heparin provides a survival benefit over previous standard thrombolytic regimens.
Recombinant tissue-type plasminogen activator and immediate angioplasty in acute myocardial infarction.
Alfred Arnold,Maarten L. Simoons,David de Bono,Jan Tijssen,Patrick Serruys,Marc Verstraete,Jacob Lubsen,Frans Van de Werf +7 more
TL;DR: In this article, the authors conducted two randomized trials in patients with suspected myocardial infarction to assess the effect of 100 mg single-chain recombinant tissue-type plasminogen activator (rt-PA, alteplase) on enzymatic infarct size, left ventricular function, morbidity and mortality relative to placebo.
Thrombolysis with rt-PA in acute myocardial infarction: no additional benefit of immediate PTCA
Maarten L. Simoons,Amadeo Betriu,M. Bokslag,David de Bono,Ronald W. Brower,J Col,F. C. Dougherty,R. Von Essen,Heinz Lambertz,Jacob Lubsen,B. Meier,Michel Pl,Philippe Raynaud,Wolfgang Rutsch,G.A. Sanz,W. Schmidt,Patrick Serruys,C. Thery,Rainer Uebis,A Vahanian,George M. Willems,David A. Wood,Marc Verstraete,Alfred Arnold,Frans Van de Werf +24 more
TL;DR: There seems to be no need for immediate angiography and PTCA in patients with acute myocardial infarction treated with rTPA, with a lower incidence of recurrent ischaemia, bleeding complications, hypotension, and ventricular fibrillation after non-invasive therapy.
Risk Factors for In-hospital Nonhemorrhagic Stroke in Patients With Acute Myocardial Infarction Treated With Thrombolysis: Results from GUSTO-I : Results From Gusto-I
Kenneth W. Mahaffey,Robert M. Califf,Christopher B. Granger,Michael A. Sloan,Trevor D. Thompson,JM Gore,W D Weaver,Harvey D. White,Maarten L. Simoons,G. I. Barbash,Eric J. Topol +10 more
TL;DR: A simple nomogram is developed that can predict the risk of nonhemorrhagic stroke on the basis of baseline clinical characteristics and prophylactic anticoagulation may be an important treatment strategy for patients with high probability for nonhemorshagic stroke.
infarction be referred for direct PTCA? Should all patients with an acute myocardial
TL;DR: This article cites 20 articles, 15 of which can be accessed free at: Rapid responses http://heart.bmjjournals.com/cgi/eletter-submit/90/11/1352/DC1 "Web-only References".