Maddalena Venturoli

TL;DR: In this article, the authors compare various strategies to coarse-grained simulation of a biological membrane and conclude that the results obtained by the various mesoscopic models are surprisingly consistent. But they do not discuss the effect of transmembrane peptides on the local structure of a membrane and the mechanism of vesicle fusion and fission.

TL;DR: A mesoscopic model for lipid bilayers with embedded proteins, which has been studied with the help of the dissipative particle dynamics simulation technique, suggests that, when the embedded protein has a small size, the main mechanism to compensate for a large hydrophobic mismatch is the tilt, whereas large proteins react to negative mismatch by causing an increase of theHydrophobic thickness of the nearby bilayer.

TL;DR: Calculations of the potential of mean force between transmembrane proteins show that hydrophobic forces drive long-range protein-protein interactions and that the nature of these interactions depends on the length of the protein Hydrophobic segment, on the three-dimensional structure of theprotein and on the properties of the lipid bilayer.

TL;DR: In this article, the influence of the molecular structure and the level of coarse graining on the bilayer properties was studied using dissipative particle dynamics combined with a Monte Carlo scheme to achieve the natural state of a tensionless bilayer.

TL;DR: In this article, the effect of changes in the chain length and stiffness of the surfactants on the properties of the model membranes are studied, and it is shown that changes of the stiffness have significant effects if these changes are made close to the head group of a surfactant.