M
Madhava C. Reddy
Researcher at Yogi Vemana University
Publications - 35
Citations - 1553
Madhava C. Reddy is an academic researcher from Yogi Vemana University. The author has contributed to research in topics: Cancer & DNA damage. The author has an hindex of 17, co-authored 34 publications receiving 1277 citations. Previous affiliations of Madhava C. Reddy include University of Hyderabad & University of Texas MD Anderson Cancer Center.
Papers
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Journal ArticleDOI
Molecular mechanisms in C-Phycocyanin induced apoptosis in human chronic myeloid leukemia cell line-K562.
Jagu Subhashini,Suraneni V.K. Mahipal,Madhava C. Reddy,Metukuri Mallikarjuna Reddy,Aparna Rachamallu,Pallu Reddanna +5 more
TL;DR: It is demonstrated that C-PC induces apoptosis in K562 cells by cytochrome c release from mitochondria into the cytosol, PARP cleavage and down regulation of Bcl-2.
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Sweeten PAMPs: Role of Sugar Complexed PAMPs in Innate Immunity and Vaccine Biology
TL;DR: Sensing of different types of glycosylated PAMPs such as β-glucan or lipopolysaccharides, nucleic acid, and so on (sugar complex PAMps) by different families of sensors, its role in pathogenesis, and its application in development of potential vaccine and vaccine adjuvants are discussed.
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C-Phycocyanin, a selective cyclooxygenase-2 inhibitor, induces apoptosis in lipopolysaccharide-stimulated RAW 264.7 macrophages.
Madhava C. Reddy,Jagu Subhashini,Suraneni V.K. Mahipal,Vadiraja B. Bhat,P Srinivas Reddy,G. Kiranmai,K.M. Madyastha,Pallu Reddanna +7 more
TL;DR: This C-PC induced apoptosis in RAW 264.7 cells appears to be mediated by the release of cytochrome c from mitochondria and independent of Bcl-2 expression, and may be due to reduced PGE(2) levels as a result of COX-2 inhibition.
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Bacterial lipopolysaccharide-induced oxidative stress in the impairment of steroidogenesis and spermatogenesis in rats.
M Mallikarjuna Reddy,Suraneni V.K. Mahipal,Jagu Subhashini,Madhava C. Reddy,Karnati R. Roy,Gorla V. Reddy,Pingili R.K. Reddy,Pallu Reddanna +7 more
TL;DR: Data from an LPS rat model are consistent with oxidative stress as a major causal factor in altered steroidogenesis, spermatogenesis, and perhaps male infertility during endotoxin-induced acute inflammation.
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Salt-tolerant genes from halophytes are potential key players of salt tolerance in glycophytes
Yeduguri Himabindu,Thammineni Chakradhar,Madhava C. Reddy,Andrey Kanygin,Kevin Redding,Thummala Chandrasekhar,Thummala Chandrasekhar +6 more
TL;DR: The transgenic overexpression of halophytic genes in crops will be discussed as a successful mechanism for the induction of salt tolerance and the advances in genetic engineering technology for the production of genetically modified crops to achieve the improved salinity tolerance under field conditions will also be discussed.