M
Magali Giral
Researcher at University of Nantes
Publications - 233
Citations - 8851
Magali Giral is an academic researcher from University of Nantes. The author has contributed to research in topics: Transplantation & Kidney transplantation. The author has an hindex of 47, co-authored 198 publications receiving 7596 citations. Previous affiliations of Magali Giral include French Institute of Health and Medical Research.
Papers
More filters
Journal ArticleDOI
Effect of long-term immunosuppression in kidney-graft recipients on cancer incidence: randomised comparison of two cyclosporin regimens
Jacques Dantal,Maryvonne Hourmant,Diego Cantarovich,Magali Giral,Gilles Blancho,Brigitte Dréno,Jean-Paul Soulillou +6 more
TL;DR: It is found that halving of trough blood cyclosporin concentrations significantly changes graft function or graft survival, and the design of long-term maintenance protocols for transplant recipients based on powerful immunosuppressant combinations should take these potential risks into account.
Journal ArticleDOI
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans
Pervinder Sagoo,Esperanza Perucha,Birgit Sawitzki,Stefan Tomiuk,David A. Stephens,Patrick Miqueu,S Chapman,Ligia Craciun,Ruhena Sergeant,Sophie Brouard,Flavia Rovis,Elvira Jimenez,Amany Ballow,Magali Giral,Irene Rebollo-Mesa,Alain Le Moine,Cécile Braudeau,Rachel Hilton,Bernhard Gerstmayer,Katarzyna Bourcier,Adnan Sharif,Magdalena Krajewska,Graham M. Lord,Ian S.D. Roberts,Michel Goldman,Kathryn J. Wood,Kenneth A. Newell,Vicki Seyfert-Margolis,Anthony N. Warrens,Uwe Janssen,Hans-Dieter Volk,Jean-Paul Soulillou,Maria P. Hernandez-Fuentes,Robert I. Lechler +33 more
TL;DR: An immunological profile of the tolerant state is provided that, with further validation, should inform and shape drug-weaning protocols in renal transplant recipients.
Journal ArticleDOI
Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance
Sophie Brouard,Elaine Mansfield,Christophe Braud,Li Li,Magali Giral,Szu-Chuan Hsieh,Dominique Baeten,Meixia Zhang,Joanna Ashton-Chess,Cécile Braudeau,Frank Hsieh,Alexandre Dupont,A. Pallier,Anne Moreau,Stéphanie Louis,Catherine Ruiz,Oscar Salvatierra,Jean-Paul Soulillou,Minnie M. Sarwal +18 more
TL;DR: This study identifies in the blood of kidney recipients a set of genes associated with operational tolerance that may have utility as a minimally invasive monitoring tool for guiding IS titration.
Journal ArticleDOI
Frequency and Clinical Implications of Development of Donor-Specific and Non–Donor-Specific HLA Antibodies after Kidney Transplantation
Maryvonne Hourmant,Anne Cesbron-Gautier,Paul I. Terasaki,Kazuo Mizutani,Anne Moreau,Aurélie Meurette,Jacques Dantal,Magali Giral,Gilles Blancho,Diego Cantarovich,Georges Karam,Gilles Folléa,Jean-Paul Soulillou,Jean-Denis Bignon +13 more
TL;DR: Screening of HLA antibodies posttransplantation could be a good tool for the follow-up of patients who receive a kidney transplant and allow immunosuppression to be tailored.
Journal ArticleDOI
Each additional hour of cold ischemia time significantly increases the risk of graft failure and mortality following renal transplantation.
Agnes Debout,Yohann Foucher,Katy Trébern-Launay,Christophe Legendre,Christophe Legendre,Henri Kreis,Henri Kreis,Georges Mourad,Valérie Garrigue,Emmanuel Morelon,Fanny Buron,Lionel Rostaing,Nassim Kamar,Michèle Kessler,Marc Ladrière,Alexandra Poignas,Amina Blidi,Jean-Paul Soulillou,Magali Giral,Etienne Dantan +19 more
TL;DR: Findings are of practical clinical interest, as cold ischemia time is among one of the main modifiable pre-transplantation risk factors that can be minimized by improved management of the peri-trans transplantation period.