Magda Beier

TL;DR: Two groups of volunteers were vaccinated by repeated exposure to the bites of Plasmodium falciparum-infected, x-irradiated mosquitoes in order to characterize the humoral and cellular immune responses of sporozoite-immunized, protected individuals.

TL;DR: Gram-negative but not gram-positive bacteria affect sporogonic-stage development of P. falciparum in A. stephensi, showing that inhibition of parasite acquisition may be an attribute of specific or nonspecific cytoadherence properties of gram-negative bacteria to the parasites.

TL;DR: The low but highly variable numbers of sporozoites transmitted in vitro by mosquitoes used in malaria vaccine challenge studies appears to be a reasonable simulation of natural sporozoite transmission.

TL;DR: Results set a new standard for persistence of sterile immunity against experimental P. falciparum malaria by showing antibodies to sporozoites circulated at high levels for at least 9-12 months after the volunteers were administered booster bites from X-irradiated infective mosquitoes.

TL;DR: The demonstration that An.