Mahboobeh Yadollahie

Bio: Mahboobeh Yadollahie is an academic researcher from National Iranian Oil Company. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 10, co-authored 37 publications receiving 559 citations.

On determining the most appropriate test cut-off value: the case of tests with continuous results

Abstract: There are several criteria for determination of the most appropriate cut-off value in a diagnostic test with continuous results. Mostly based on receiver operating characteristic (ROC) analysis, there are various methods to determine the test cut-off value. The most common criteria are the point on ROC curve where the sensitivity and specificity of the test are equal; the point on the curve with minimum distance from the left-upper corner of the unit square; and the point where the Youden's index is maximum. There are also methods mainly based on Bayesian decision analysis. Herein, we show that a proposed method that maximizes the weighted number needed to misdiagnose, an index of diagnostic test effectiveness we previously proposed, is the most appropriate technique compared to the aforementioned ones. For determination of the cut-off value, we need to know the pretest probability of the disease of interest as well as the costs incurred by misdiagnosis. This means that even for a certain diagnostic test, the cut-off value is not universal and should be determined for each region and for each disease condition.

Are shorter article titles more attractive for citations? Cross-sectional study of 22 scientific journals.

Abstract: Aim To investigate the correlation between the length of the title of a scientific article and the number of citations it receives, in view of the common editorial call for shorter titles.

Rate of re-positive RT-PCR test among patients recovered from COVID-19.

Abstract: 1Persian BayanGene Research and Training Center, Shiraz University of Medical Sciences, Shiraz, Iran 2Institute of Human Virology, University of Maryland School of Medicine, Baltimore, United States of America 3Burn and Wound Healing Research Center, Microbiology Department, Shiraz University of Medical Sciences, Shiraz, Iran 4Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 5R&D Headquarters, Petroleum Industry Health Organization, Shiraz, Iran 6Department of Nursing, Larestan University of Medical Sciences, Larestan, Iran

Global epidemiology of atrial fibrillation

Abstract: Atrial fibrillation (AF) is a major public health burden worldwide, and its prevalence is set to increase owing to widespread population ageing, especially in rapidly developing countries such as Brazil, China, India, and Indonesia. Despite the availability of epidemiological data on the prevalence of AF in North America and Western Europe, corresponding data are limited in Africa, Asia, and South America. Moreover, other observations suggest that the prevalence of AF might be underestimated-not only in low-income and middle-income countries, but also in their high-income counterparts. Future studies are required to provide precise estimations of the global AF burden, identify important risk factors in various regions worldwide, and take into consideration regional and ethnic variations in AF. Furthermore, in response to the increasing prevalence of AF, additional resources will need to be allocated globally for prevention and treatment of AF and its associated complications. In this Review, we discuss the available data on the global prevalence, risk factors, management, financial costs, and clinical burden of AF, and highlight the current worldwide inadequacy of its treatment.

On determining the most appropriate test cut-off value: the case of tests with continuous results

Abstract: There are several criteria for determination of the most appropriate cut-off value in a diagnostic test with continuous results. Mostly based on receiver operating characteristic (ROC) analysis, there are various methods to determine the test cut-off value. The most common criteria are the point on ROC curve where the sensitivity and specificity of the test are equal; the point on the curve with minimum distance from the left-upper corner of the unit square; and the point where the Youden's index is maximum. There are also methods mainly based on Bayesian decision analysis. Herein, we show that a proposed method that maximizes the weighted number needed to misdiagnose, an index of diagnostic test effectiveness we previously proposed, is the most appropriate technique compared to the aforementioned ones. For determination of the cut-off value, we need to know the pretest probability of the disease of interest as well as the costs incurred by misdiagnosis. This means that even for a certain diagnostic test, the cut-off value is not universal and should be determined for each region and for each disease condition.

Norms for Zung’s Self-rating Anxiety Scale

Abstract: Zung’s Self-rating Anxiety Scale (SAS) is a norm-referenced scale which enjoys widespread use a screener for anxiety disorders. However, recent research (Dunstan DA and Scott N, Depress Res Treat 2018:9250972, 2018) has questioned whether the existing cut-off for identifying the presence of a disorder might be lower than ideal. The current study explored this issue by examining sensitivity and specificity figures against diagnoses made on the basis of the Patient Health Questionnaire (PHQ) in clinical and community samples. The community sample consisted of 210 participants recruited to be representative of the Australian adult population. The clinical sample consisted of a further 141 adults receiving treatment from a mental health professional for some form of anxiety disorder. Mathematical formulas, including Youden’s Index and the Receiver Operating Characteristics Curve, applied to positive PHQ diagnoses (presence of a disorder) from the clinical sample and negative PHQ diagnoses (absence of a disorder) from the community sample suggested that the ideal cut-off point lies between the current and original points recommended by Zung. Consideration of prevalence rates and of the potential costs of false negative and false positive diagnoses, suggests that, while the current cut-off of 36 might be appropriate in the context of clinical screening, the original raw score cut-off of 40 would be most appropriate when the SAS is used in research.

Popular and/or prestigious? Measures of scholarly esteem

Abstract: Citation analysis does not generally take the quality of citations into account: all citations are weighted equally irrespective of source. However, a scholar may be highly cited but not highly regarded: popularity and prestige are not identical measures of esteem. In this study we define popularity as the number of times an author is cited and prestige as the number of times an author is cited by highly cited papers. Information retrieval (IR) is the test field. We compare the 40 leading researchers in terms of their popularity and prestige over time. Some authors are ranked high on prestige but not on popularity, while others are ranked high on popularity but not on prestige. We also relate measures of popularity and prestige to date of Ph.D. award, number of key publications, organizational affiliation, receipt of prizes/honors, and gender.

Deep learning as a predictive tool for fetal heart pregnancy following time-lapse incubation and blastocyst transfer

Abstract: STUDY QUESTION Can a deep learning model predict the probability of pregnancy with fetal heart (FH) from time-lapse videos?