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Mahjabeen Khan

Other affiliations: Vision-Sciences, Inc.
Bio: Mahjabeen Khan is an academic researcher from University of New South Wales. The author has contributed to research in topics: Tobramycin & Integron. The author has an hindex of 5, co-authored 12 publications receiving 154 citations. Previous affiliations of Mahjabeen Khan include Vision-Sciences, Inc..

Papers
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Journal ArticleDOI
TL;DR: The study concluded that individuals belonging to the front‐line workers and high literacy groups are not prepared for the alarming situation in the country and effective implementation of infection control programs should be practiced.
Abstract: COVID-19 is a pandemic that began in China in December 2019. World health organization (WHO) has expressed fears that Pakistan might emerge as the next epicenter of this pandemic. We hypothesize that at present the Pakistani masses are not prepared to face any threat of a looming epidemic. The main aim of this study was to evaluate the basic knowledge of educational and health care workers (HCWs) regarding COVID-19, its control, and prevention. Knowledge about origin, symptoms, and spread of viral infection was assessed. In this cross-sectional survey, a self-designed questionnaire was distributed among 302 HCWs including physicians (10.9%), nurses (1.32%), lab staff (1.65%), and academic individuals including faculty and students (86.42%) of different organizations. Results were analyzed using the χ2 test. Obtained results validate our null hypothesis that Pakistani masses are not well aware of the COVID-19 and strategies for the prevention and control of infection. The study concluded that individuals belonging to the front-line workers and high literacy groups are not prepared for the alarming situation in the country. Effectual implementation of infection control programs should be practiced, and it depends on awareness, training, and cooperation of individuals.

74 citations

Journal ArticleDOI
TL;DR: In this article, the frequency dependent anisotropic dielectric functions were calculated using the self-consistent potentials and the full potential linear augmented plane-wave (FPLAPW) method.
Abstract: We have calculated the electronic band structure of $2H\ensuremath{-}{\mathrm{WSe}}_{2},$ within the local-density approximation using the linear muffin-tin orbital method in the atomic sphere approximation as well as the full potential linear augmented plane-wave (FPLAPW) method. Using the self-consistent potentials, we have calculated the frequency dependent anisotropic dielectric functions ${\ensuremath{\epsilon}}^{\ensuremath{\Vert}}(\ensuremath{\omega})$ and ${\ensuremath{\epsilon}}^{\ensuremath{\perp}}(\ensuremath{\omega})$ corresponding to the electric field parallel and perpendicular to the $c$ axis. The results of these calculations are compared with experimental data and show better agreement for the FPLAPW calculation. We have included the spin-orbit coupling in the calculation of the frequency dependent dielectric function using the FPLAPW and find the effect to be small.

55 citations

Journal ArticleDOI
TL;DR: Overall, the Indian isolates were resistant to more antibiotics, with some of those isolates being multi-drug resistant, and large number of acquired resistance genes, greater changes to MMR genes, and a larger pan genome as well as increased overall genetic variation are investigated.
Abstract: This study investigated genomic differences in Australian and Indian Pseudomonas aeruginosa isolates from keratitis (infection of the cornea). Overall, the Indian isolates were resistant to more antibiotics, with some of those isolates being multi-drug resistant. Acquired genes were related to resistance to fluoroquinolones, aminoglycosides, beta-lactams, macrolides, sulphonamides, and tetracycline and were more frequent in Indian (96%) than in Australian (35%) isolates (p = 0.02). Indian isolates had large numbers of gene variations (median 50,006, IQR = 26,967-50,600) compared to Australian isolates (median 26,317, IQR = 25,681-33,780). There were a larger number of mutations in the mutL and uvrD genes associated with the mismatch repair (MMR) system in Indian isolates, which may result in strains losing their efficacy for DNA repair. The number of gene variations were greater in isolates carrying MMR system genes or exoU. In the phylogenetic division, the number of core genes were similar in both groups, but Indian isolates had larger numbers of pan genes (median 6518, IQR = 6040-6935). Clones related to three different sequence types-ST308, ST316, and ST491-were found among Indian isolates. Only one clone, ST233, containing two strains was present in Australian isolates. The most striking differences between Australian and Indian isolates were carriage of exoU (that encodes a cytolytic phospholipase) in Indian isolates and exoS (that encodes for GTPase activator activity) in Australian isolates, large number of acquired resistance genes, greater changes to MMR genes, and a larger pan genome as well as increased overall genetic variation in the Indian isolates.

22 citations

Journal ArticleDOI
01 Mar 2000-Pramana
TL;DR: In this article, anisotropic frequency dependent dielectric function for the 1T and 2H phases of TaS2 and TaSe2 was calculated using the linear muffin tin orbital method within the atomic sphere approximation.
Abstract: We have calculated the anisotropic frequency dependent dielectric function for the 1T and 2H phases of TaS2 and TaSe2 using the linear muffin tin orbital method within the atomic sphere approximation. We find significant anisotropy in the frequency dependent dielectric function for the 1T and 2H phases at low energies (less than 4 eV). Unfortunately there are no experimental data to compare with. The averaged dielectric function agrees with the available experimental data except that the calculated peak heights are underestimated and shifted to higher energies by 1–2eV.

20 citations

Journal ArticleDOI
TL;DR: The presence of crpP on its own was not associated with increased resistance to fluoroquinolones, and mutations in quinolone resistance determining regions (QRDRs) and antibiotic susceptibilities to ciprofloxacin, levofloxacins and moxifl oxacin were assessed to examine the association between resistance genes and phenotype.

16 citations


Cited by
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01 Jun 2012
TL;DR: SPAdes as mentioned in this paper is a new assembler for both single-cell and standard (multicell) assembly, and demonstrate that it improves on the recently released E+V-SC assembler and on popular assemblers Velvet and SoapDeNovo (for multicell data).
Abstract: The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagenomic data with whole-genome assemblies of uncultivated organisms. Assembly of single-cell data is challenging because of highly non-uniform read coverage as well as elevated levels of sequencing errors and chimeric reads. We describe SPAdes, a new assembler for both single-cell and standard (multicell) assembly, and demonstrate that it improves on the recently released E+V-SC assembler (specialized for single-cell data) and on popular assemblers Velvet and SoapDeNovo (for multicell data). SPAdes generates single-cell assemblies, providing information about genomes of uncultivatable bacteria that vastly exceeds what may be obtained via traditional metagenomics studies. SPAdes is available online ( http://bioinf.spbau.ru/spades ). It is distributed as open source software.

10,124 citations

Journal ArticleDOI
Hong Jiang1
TL;DR: In this paper, quasi-particle electronic properties of these materials are investigated by many-body perturbation theory in the GW approximation, currently the most accurate first-principles approach for electronic band structure of extended systems.
Abstract: Molybdenum and tungsten dichalcogenides, MX2 (M = Mo and W; X = S and Se), characterized by their quasi-two-dimensional layered structure, have attracted intensive interest due to their intriguing physical and chemical properties. In this work, quasi-particle electronic properties of these materials are investigated by many-body perturbation theory in the GW approximation, currently the most accurate first-principles approach for electronic band structure of extended systems. It is found that the fundamental band gaps of all of these materials can be well described by the GW approach, and the calculated density of states from GW quasi-particle band energies agree very well with photoemission spectroscopy data. Ionization potentials of these materials are also studied by combining the slab model using density functional theory and GW correction. On the basis of our theoretical findings, we predict that none of the materials in MX2 (M = Zr, Hf, Mo, and W; X = S and Se) in their bulk form can be directly use...

262 citations

Journal ArticleDOI
TL;DR: In this article, the optical properties of perovskite barium titanate in the core-level spectra were investigated by the first principles under scissor approximation, and the optical spectra are assigned to interband contribution from O 2p valence bands to Ti 3d conduction bands in the low energy region and outer core electron excitation (core level excitation) from near valence band semicore levels Ba 5p and O 2s to conduction band in the high energy region.
Abstract: The optical properties of perovskite barium titanate in the core-level spectra are investigated by the first principles under scissor approximation. There are nine peaks at the curve of the imaginary part of dielectric function. The optical spectra are assigned to interband contribution from O 2p valence bands to Ti 3d conduction bands in the low-energy region and outer core electron excitation (core level excitation) from near valence band semicore levels Ba 5p and O 2s to conduction band in the high-energy region. In contrast to the calculated results by the tight-binding linear muffin-tin orbitals method, our results are in better agreement with the experimental results.

192 citations

Journal ArticleDOI
TL;DR: In this article, the exchange-correlation potential is treated by the generalized gradient approximation (GGA) within the scheme of J. P. Perdew, K. Burke, and M. H. Ernzerhof.
Abstract: Optical properties of strontium monochalcogenide compounds SrX ($\mathrm{X}=\mathrm{Se}$, Se, and Te) in NaCl crystal structure are calculated using the band structure results obtained through the full potential linearized augmented plane wave method. The exchange-correlation potential is treated by the generalized gradient approximation (GGA) within the scheme of J. P. Perdew, K. Burke, and M. Ernzerhof [Phys. Rev. Lett. 77, 3865 (1996)]. Also we have used Engel and Vosko GGA formalism [E. Engel and S. H. Vosko, Phys. Rev. B. 47, 13164 (1993)] to improve the band gap results. The real and imaginary parts of the dielectric function $\ensuremath{\epsilon}(\ensuremath{\omega})$, the optical absorption coefficient $I(\ensuremath{\omega})$, the reflectivity $R(\ensuremath{\omega})$ and the energy loss function are calculated. The calculated results show good agreement with the available experimental results, particularly in the low energy region of the spectra. Furthermore, the interband transitions responsible for the structures in the spectra are specified. It is shown that the chalcogen $p$ states and Sr $4d$ states play the major role in optical transitions as initial and final states, respectively. The effect of the spin-orbit coupling on the optical properties is also investigated and found to be quite small, especially in the low energy region.

126 citations

Journal ArticleDOI
TL;DR: In this article, the structural, electronic, and optical properties of multiferroic bismuth ferrite (BiFeO3) were investigated using density functional theory within generalized gradient approximation (GGA).

117 citations