Mahmoud Roushani

Bio: Mahmoud Roushani is an academic researcher from Razi University. The author has contributed to research in topics: Electrode & Aptamer. The author has an hindex of 30, co-authored 156 publications receiving 3094 citations. Previous affiliations of Mahmoud Roushani include University of Kurdistan.

Graphene quantum dots as novel and green nano-materials for the visible-light-driven photocatalytic degradation of cationic dye

Abstract: In this paper, we have introduced a novel property of graphene quantum dots (GQDs) as efficient nano-materials for degradation of organic pollutant dyes based on the photocatalytic behavior of GQDs under visible light irradiation GQD samples were synthesized directly through pyrolyzing citric acid method The synthesized GQDs were characterized by various techniques including colorimetry, transmission electron microscopy (TEM), and UV–vis absorption, Raman spectroscopy, fluorescence spectroscopy, and zeta potential measurements In this study, a cationic dye (ie, New Fuchsin) was chosen as a model molecule to investigate catalytic behavior of the prepared GQDs as green nanomaterials The influence of experimental parameters such as pH of the dye solution, contacting time, dosage of GQDs, and initial concentration of NF dye on the degradation efficiency of GQD were studied The possible mechanisms of degradation of NF based on GQDs under visible light were discussed, too

Electrochemical immunosensor with Cu 2 O nanocube coating for detection of SARS-CoV-2 spike protein.

Abstract: Severe acute respiratory syndrome SARS-CoV-2 has caused a global pandemic starting in 2020. Accordingly, testing is crucial for mitigating the economic and public health effects. In order to facilitate point-of-care diagnosis, this study aims at presenting a label-free electrochemical biosensor as a powerful nanobiodevice for SARS-CoV-2 spike protein detection. Utilizing the IgG anti-SARS-CoV-2 spike antibody onto the electrode surface as a specific platform in an ordered orientation through staphylococcal protein A (ProtA) is highly significant in fabricating the designed nanobiodevice. In this sense, the screen-printed carbon electrode modified with Cu2O nanocubes (Cu2O NCs), which provide a large surface area in a very small space, was applied in order to increase the ProtA loading on the electrode surface. Accordingly, the sensitivity and stability of the sensing platform significantly increased. The electrochemical evaluations proved that there is a very good linear relationship between the charge transfer resistance (Rct) and spike protein contents via a specific binding reaction in the range 0.25 fg mL−1 to 1 μg mL−1. Moreover, the assay when tested with influenza viruses 1 and 2 was performed in 20 min with a low detection limit of 0.04 fg mL−1 for spike protein without any cross-reactivity. The designed nanobiodevice exhibited an average satisfactory recovery rate of ~ 97–103% in different artificial sample matrices, i.e., saliva, artificial nasal, and universal transport medium (UTM), illustrating its high detection performance and practicability. The nanobiodevice was also tested using real patients and healthy samples, where the results had been already obtained using the standard polymerase chain reaction (PCR) procedure, and showed satisfactory results.

A comprehensive review of glucose biosensors based on nanostructured metal-oxides.

Abstract: Nanotechnology has opened new and exhilarating opportunities for exploring glucose biosensing applications of the newly prepared nanostructured materials. Nanostructured metal-oxides have been extensively explored to develop biosensors with high sensitivity, fast response times, and stability for the determination of glucose by electrochemical oxidation. This article concentrates mainly on the development of different nanostructured metal-oxide [such as ZnO, Cu(I)/(II) oxides, MnO2, TiO2, CeO2, SiO2, ZrO2, and other metal-oxides] based glucose biosensors. Additionally, we devote our attention to the operating principles (i.e., potentiometric, amperometric, impedimetric and conductometric) of these nanostructured metal-oxide based glucose sensors. Finally, this review concludes with a personal prospective and some challenges of these nanoscaled sensors.

Recent Advances on Graphene Quantum Dots: From Chemistry and Physics to Applications

Abstract: Graphene quantum dots (GQDs) that are flat 0D nanomaterials have attracted increasing interest because of their exceptional chemicophysical properties and novel applications in energy conversion and storage, electro/photo/chemical catalysis, flexible devices, sensing, display, imaging, and theranostics. The significant advances in the recent years are summarized with comparative and balanced discussion. The differences between GQDs and other nanomaterials, including their nanocarbon cousins, are emphasized, and the unique advantages of GQDs for specific applications are highlighted. The current challenges and outlook of this growing field are also discussed.