M
Mala T. Kailasam
Researcher at University of California, San Diego
Publications - 23
Citations - 1231
Mala T. Kailasam is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Essential hypertension & Blood pressure. The author has an hindex of 17, co-authored 23 publications receiving 1194 citations. Previous affiliations of Mala T. Kailasam include University of California & Veterans Health Administration.
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Journal ArticleDOI
Plasma Hydrogen Peroxide Production in Human Essential Hypertension Role of Heredity, Gender, and Ethnicity
TL;DR: Results indicate that hydrogen peroxide production is heritable and is related to target organ function in essential hypertension, and genetic loci influencing hydrogenperoxide production may represent logical candidates to investigate as susceptibility genes for cardiovascular target organ injury.
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Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension.
Daniel T. O'Connor,Mala T. Kailasam,Brian P. Kennedy,Michael G. Ziegler,Noboru Yanaihara,Robert J. Parmer +5 more
TL;DR: It is concluded that catestatin is diminished early in the course of development of hypertension, even in the normotensive offspring of patients with the disease.
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Development and validation of a noninvasive method to determine arterial pressure and vascular compliance
Todd J. Brinton,Bruno Cotter,Mala T. Kailasam,David L. Brown,Shiu-Shin Chio,Daniel T. O'Connor,Anthony N. DeMaria +6 more
TL;DR: The measurement of absolute pressure and rate of pressure change show good correlation with catheter data and that vascular compliance can be reliably assessed by this new method, and the technology should provide a valuable noninvasive tool for the assessment of both cardiac function and vascular properties.
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Chromogranin A in Human Hypertension: Influence of Heredity
Marwan A. Takiyyuddin,Robert J. Parmer,Mala T. Kailasam,Justine H. Cervenka,Brian K. Kennedy,Michael G. Ziegler,Ming-Cheng Lin,Jing Li,Clarence E. Grim,Fred A. Wright,Daniel T. O'Connor +10 more
TL;DR: It is concluded that plasma chromogranin A displays substantial heritability and is increased in established essential hypertension, and its elevation in established hypertension is associated with evidence of increased vesicular stores of the protein and with adrenergic hyperactivity.
Journal ArticleDOI
Divergent effects of dihydropyridine and phenylalkylamine calcium channel antagonist classes on autonomic function in human hypertension
Mala T. Kailasam,Robert J. Parmer,Justine H. Cervenka,Regina A. Wu,Michael G. Ziegler,Brian P. Kennedy,Isaac A. Adegbile,Daniel T. O'Connor +7 more
TL;DR: Comparing acute and chronic effects of two classes of calcium channel antagonists, the dihydropyridine type (felodipine) and the phenylalkylamine type (verapamil), on efferent sympathetic outflow and baroreflex slope in 15 essential hypertensive subjects found that the corresponding changes were closely similar to those after placebo.