M
Malgorzata E. Wilinska
Researcher at University of Cambridge
Publications - 127
Citations - 6555
Malgorzata E. Wilinska is an academic researcher from University of Cambridge. The author has contributed to research in topics: Type 1 diabetes & Diabetes mellitus. The author has an hindex of 39, co-authored 105 publications receiving 5773 citations. Previous affiliations of Malgorzata E. Wilinska include Wellcome Trust & National Institute for Health Research.
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Journal ArticleDOI
Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes
Roman Hovorka,Valentina Canonico,Ludovic J. Chassin,Ulrich Haueter,Massimo Massi-Benedetti,Marco Orsini Federici,Thomas R. Pieber,Helga C. Schaller,Lukas Schaupp,Thomas Vering,Malgorzata E. Wilinska +10 more
TL;DR: Adapt nonlinear model predictive control is promising for the control of glucose concentration during fasting conditions in subjects with type 1 diabetes.
Journal ArticleDOI
Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial
Roman Hovorka,Janet M. Allen,Daniela Elleri,Ludovic J. Chassin,Julie Harris,Dongyuan Xing,Craig Kollman,Tomas Hovorka,Anne Mette F. Larsen,Marianna Nodale,Alessandra De Palma,Malgorzata E. Wilinska,Carlo L. Acerini,David B. Dunger +13 more
TL;DR: Whether closed-loop insulin delivery could control overnight blood glucose in young people with type 1 diabetes and reduce risk of nocturnal hypoglycaemia in children and adolescents with type 2 diabetes is established.
Journal ArticleDOI
Insulin kinetics in type-1 diabetes: continuous and bolus delivery of rapid acting insulin
Malgorzata E. Wilinska,Ludovic J. Chassin,Helga C. Schaller,Lukas Schaupp,Thomas R. Pieber,Roman Hovorka +5 more
TL;DR: Models representing the dependence of insulin absorption rate on insulin disappearance and the remote insulin effect on its volume of distribution could not be validated suggesting that these effects are not present or cannot be detected during physiological conditions.
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Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies
Roman Hovorka,Kavita Kumareswaran,Julie Harris,Janet M. Allen,Daniela Elleri,Dongyuan Xing,Craig Kollman,Marianna Nodale,Helen R. Murphy,David B. Dunger,Stephanie A. Amiel,Simon Heller,Malgorzata E. Wilinska,Mark L. Evans +13 more
TL;DR: It is suggested that closed loop delivery of insulin may improve overnight control of glucose levels and reduce the risk of nocturnal hypoglycaemia in adults with type 1 diabetes.
Journal ArticleDOI
Simulation Environment to Evaluate Closed-Loop Insulin Delivery Systems in Type 1 Diabetes
Malgorzata E. Wilinska,Ludovic J. Chassin,Carlo L. Acerini,Janet M. Allen,David B. Dunger,Roman Hovorka +5 more
TL;DR: Close-loop trials in humans should be preceded and concurrently guided by highly efficient and resource-saving computer-based simulations, and validity of population-based predictions obtained with the simulation environment is demonstrated.