Author
Manish Dixit
Other affiliations: Harcourt Butler Technological Institute, Dharamsinh Desai University, Science Applications International Corporation ...read more
Bio: Manish Dixit is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Catalysis & Ring (chemistry). The author has an hindex of 17, co-authored 37 publications receiving 816 citations. Previous affiliations of Manish Dixit include Harcourt Butler Technological Institute & Dharamsinh Desai University.
Topics: Catalysis, Ring (chemistry), Pyran, Medicine, Cancer
Papers
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TL;DR: The ultimate goal of this perspective is to introduce inorganic chemists to the field of nuclear medicine and radiopharmaceutical development, where many applications of fundamental inorganic chemistry can be found.
Abstract: Metallic radionuclides are the mainstay of both diagnostic and therapeutic radiopharmaceuticals. Therapeutic nuclear medicine is less advanced but has tremendous potential if the radionuclide is accurately targeted. Great interest exists in the field of inorganic chemistry for developing target specific radiopharmaceuticals based on radiometals for non-invasive disease detection and cancer radiotherapy. This perspective will focus on the nuclear properties of a few important radiometals and their recent applications to developing radiopharmaceuticals for imaging and therapy. Other topics for discussion will include imaging techniques, radiotherapy, analytical techniques, and radiation safety. The ultimate goal of this perspective is to introduce inorganic chemists to the field of nuclear medicine and radiopharmaceutical development, where many applications of fundamental inorganic chemistry can be found.
127 citations
TL;DR: The typical and atypical imaging features of EPTB are reviewed, and the roles of several imaging modalities for the diagnosis and management of E PTB are discussed.
74 citations
TL;DR: Three of the test compounds, 2-methyl-4,5-diphenyl-3-substituted-phenyl-1H-pyrroles (3c, d and h) showed significant inhibition on postprandial hyperglycemia in normal rats post sucrose loaded.
70 citations
TL;DR: In this paper, the catalytic activity of Mg-Al hydrotalcite supported copper catalyst was investigated for clean C C and C N bond forming reactions using alcohols as alkylating agent via borrowing hydrogen methodology.
70 citations
TL;DR: It is demonstrated that the "green light" emitting fluorenones 7 can be converted to "blue light" emitters 10 by appropriate positioning of donor-acceptor and chromophoric groups onto the fluorene/fluorenone backbone.
60 citations
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1,404 citations
TL;DR: In this paper, the authors present an overview of the relationship between organic chemistry and natural products, focusing on the Stereochemistry and the Chemistry of Natural Products (SCHP).
Abstract: Organic Chemistry By Dr. I. L. Finar. Vol. 2: Stereochemistry and the Chemistry of Natural Products. Pp. xi + 733. (London and New York: Longmans, Green and Co., Ltd., 1956.) 40s. net.
1,037 citations
TL;DR: Acyclic activated alkenes/ alkynes and Asymmetric Baylis-Hillman Reaction: Earlier Developments 5495.
Abstract: 2. Essential Components: Earlier Developments 5449 2.1. Activated alkenes/alkynes 5450 2.1.1. Acyclic activated alkenes/ alkynes 5450 2.1.2. Cyclic activated alkenes 5451 2.2. Electrophiles 5451 2.3. Catalysts 5452 3. Essential Components: Recent Developments 5452 3.1. Activated Alkenes/Alkynes 5452 3.2. Electrophiles 5460 3.3. Catalysts 5477 4. Asymmetric Baylis-Hillman Reaction: Earlier Developments 5495
752 citations
580 citations
TL;DR: The design and applications of various kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved photoluminescence techniques are summarized and the imaging contrast and sensing sensitivity are remarkably improved.
Abstract: In this Review article, we systematically summarize the design and applications of various kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved photoluminescence techniques The probes reviewed, including lanthanides, transition-metal complexes, organic dyes, carbon and silicon nanoparticles, metal clusters, and persistent phosphores, exhibit longer luminescence lifetimes than that of autofluorescence from biological tissue and organs When these probes are internalized into living cells or animals, time-gated photoluminescence imaging selectively collects long-lived signals for intensity analysis, while photoluminescence lifetime imaging reports the decay details of each pixel Since the long-lived signals are differentiated from autofluorescence in the time domain, the imaging contrast and sensing sensitivity are remarkably improved The future prospects and challenges in this rapidly growing field are addressed
560 citations