M
Manisha Ahir
Researcher at University of Calcutta
Publications - 20
Citations - 505
Manisha Ahir is an academic researcher from University of Calcutta. The author has contributed to research in topics: Apoptosis & In vivo. The author has an hindex of 12, co-authored 17 publications receiving 342 citations.
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Journal ArticleDOI
PEGylated-thymoquinone-nanoparticle mediated retardation of breast cancer cell migration by deregulation of cytoskeletal actin polymerization through miR-34a.
Saurav Bhattacharya,Manisha Ahir,Prasun Patra,Sudeshna Mukherjee,Swatilekha Ghosh,Minakshi Mazumdar,Sreya Chattopadhyay,Tanya Das,Dhrubajyoti Chattopadhyay,Arghya Adhikary +9 more
TL;DR: There is direct evidence that TQ-Nps showed more efficiency in killing cancer cells as well as proved to be less toxic to normal cells at a significantly lower dose than TQ, and evaluation of the anti-migratory effect of the TQ -Nps revealed that PEG4000-TQ-nps showed much potent anti-Migratory properties than the other types.
Journal ArticleDOI
Tailored-CuO-nanowire decorated with folic acid mediated coupling of the mitochondrial-ROS generation and miR425-PTEN axis in furnishing potent anti-cancer activity in human triple negative breast carcinoma cells.
Manisha Ahir,Saurav Bhattacharya,Soumendu Karmakar,Ayan Mukhopadhyay,Sudeshna Mukherjee,Swatilekha Ghosh,Sreya Chattopadhyay,Prasun Patra,Arghya Adhikary +8 more
TL;DR: A targeted CuO Nanowire fabricated with Folic acid that enables enhanced cellular uptake in TNBC cells without imparting significant toxicity in normal cellular system is developed and raises the possibility for the use of CuO-Nw-FA as a potent anti-tumor agent.
Journal ArticleDOI
Delivery of Dual miRNA Through CD44-targeted Mesoporous Silica Nanoparticles for Enhanced and Effective Triple-Negative Breast Cancer Therapy
Manisha Ahir,Priyanka Upadhyay,Avijit Ghosh,Sushmita Sarker,Saurav Bhattacharya,Payal Gupta,Swatilekha Ghosh,Sreya Chattopadhyay,Arghya Adhikary +8 more
TL;DR: In vitro and in vivo studies demonstrated high specificity in TNBC tumor targeting, leading to efficient tumor growth inhibition as well as the retardation of metastasis, which affirmed the clinical application potential of the system.
Journal ArticleDOI
Delivery of thymoquinone through hyaluronic acid-decorated mixed Pluronic® nanoparticles to attenuate angiogenesis and metastasis of triple-negative breast cancer.
Saurav Bhattacharya,Avijit Ghosh,Santanu Maiti,Manisha Ahir,Gouranga H. Debnath,Payal Gupta,Mousumi Bhattacharjee,Swatilekha Ghosh,Sreya Chattopadhyay,Prasun Mukherjee,Arghya Adhikary +10 more
TL;DR: An innovative targeted nano-therapeutic approach is being established to reduce the tumor burden and inhibit metastasis and angiogenesis simultaneously for better management of TNBC.
Journal ArticleDOI
Improvement of Anticancer Drug Release by Cobalt Ferrite Magnetic Nanoparticles through Combined pH and Temperature Responsive Technique
Chaitali Dey,Arup Ghosh,Manisha Ahir,Ajay Ghosh,Madhuri Mandal Goswami,Madhuri Mandal Goswami +5 more
TL;DR: It was confirmed that CFMNPs are nontoxic and biocompatible in nature, which assures that the synthesized particles can be successfully used in localized cancer treatment by stimuli responsive drug delivery technique.