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Author

Manisha Pal

Bio: Manisha Pal is an academic researcher from University of Calcutta. The author has contributed to research in topic(s): Optimal design & Mixture model. The author has an hindex of 15, co-authored 84 publication(s) receiving 861 citation(s).
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Journal ArticleDOI
Abstract: In this paper we study the family of distributions termed as exponentiated Weibull distribution. The distribution has three parameters (one scale and two shape) and the Weibull distribution and the exponentiated exponential distribution, discussed by Gupta, et al. (1998), are particular cases of it. The survival function, failure rate and moments of the distributions have been derived using certain special formulas. The behavior of the failure rate has been studied and compared with those of the Weibull and Gamma distributions. The distribution has been fitted to a real life data set and the fit has been found to be very good.

132 citations


Journal ArticleDOI
TL;DR: The study suggested that smoking is associated with altered semen quality, endocrine hormonal status, and number of CAG repeats in the AR gene.
Abstract: This study was conducted as part of an epidemiological survey of 126 nonsmokers and 178 smokers, showing primary infertility residing around Kolkata region of Eastern India. Their lifestyle history including smoking habits along with semen and blood were collected. The study examined the association of cigarette smoking with the risk of infertility, by determining the semen quality, follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone levels, and androgen receptor (AR)-CAG repeat length in a group of smokers compared with a control group (non smokers). Based on conventional WHO criteria, lower sperm motility (P < 0.001) and increased sperm morphological defects (P < 0.0001) were associated with smoking habits. Binary logistic regression analysis for the effect of smoking status on sperm DNA integrity demonstrated significant positive correlation (p = 0.006). Serum FSH and LH levels were higher for smokers compared with non-smokers while the testosterone level decreased significantly ...

95 citations


Journal ArticleDOI
TL;DR: Sperm assessment for DNA status using AO is reliable and shows good correlation with sperm count, motility and morphology, and assessment of sperm DNA status with AO staining may be helpful prior to ART.
Abstract: Reports indicate an increase in the incidence of DNA fragmentation in male factor infertility and its role in the outcome of assisted reproductive techniques (ART). However, reports are conflicting between the relationships of sperm DNA integrity with conventional semen parameters. We examined the relationship between conventional sperm parameters and DNA integrity using acridine orange (AO) test. The study included 373 patients and 28 fertile volunteers. DNA normality was compared with semen parameters between the patient and donor populations. Significant correlations were noted between DNA normality and sperm concentration (r = 0.18, P = 0.000), motility (r = 0.21, P = 0.0001), rapid motility (0.19, P = 0.000), normal morphology by World Health Organization (r = 0.15, P = 0.019) and head defects (r = -0.15, P = 0.023). A significant difference was noted in AO levels between donors and patients with asthenozoospermia (P = 0.002) and oligoasthenozoospermia (P = 0.001). A significant difference in DNA integrity was noted in samples having 30% normal morphology. A wide range of % DNA normality was observed in the patient group. Sperm assessment for DNA status using AO is reliable and shows good correlation with sperm count, motility and morphology. Assessment of sperm DNA status with AO staining may be helpful prior to ART.

65 citations


Journal ArticleDOI
TL;DR: A significant decline was seen in sperm motility parameters and seminal volume in the present decade and the age-related changes in semen parameters are also different in the two decades.
Abstract: Objective To compare the semen quality and age-specific changes in men between the 1980s and 2000s. Design Prospective study. Setting Andrology laboratory, University of Calcutta, India. Patient(s) A semen sample was obtained from 3729 men presenting for infertility problems in two distinct decades, that is, between 1981–85 and 2000–2006. Intervention(s) Subjects with sperm count >20 × 10 6 /mL without any extreme pathological disorders were selected. Samples having a major liquefaction problem were excluded. Main Outcome Measure(s) A standard World Health Organization procedure for semen analysis was performed that included assessment of volume, sperm concentration, and percentage motility. The motility parameters were further classified into forward progressive motility and nonprogressive motility. Result(s) The present large-scale study confirms a significant decline in the sperm motility parameters and seminal volume in the present decade. However, no change in overall sperm concentration was noted. A decline was seen in sperm motility with increasing age in both decades. Conclusion(s) There are significant changes in sperm motility and volume between the two decades, and the age-related changes in semen parameters are also different in the two decades.

57 citations


Journal ArticleDOI
Abstract: The paper introduces a beta transmuted Weibull distribution, which contains a number of distributions as special cases. The properties of the distribution are discussed and explicit expressions are derived for the mean deviations, Bonferroni and Lorenz curves, and reliability. The distribution and moments of order statistics are also studied. Estimation of the model parameters by the method of maximum likelihood is discussed. The log beta transmuted Weibull model is introduced to analyze censored data. Finally, the usefulness of the new distribution in analyzing positive data is illustrated.

29 citations


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Journal ArticleDOI
TL;DR: The motivations, extensions and generalizations of various models in each sub-class have been discussed in brief to bring out pertinent information regarding model developments in the last decade.
Abstract: This paper presents a review of the advances of deteriorating inventory literature since the early 1990s. The models available in the relevant literature have been suitably classified by the shelf-life characteristic of the inventoried goods. They have further been sub-classified on the basis of demand variations and various other conditions or constraints. The motivations, extensions and generalizations of various models in each sub-class have been discussed in brief to bring out pertinent information regarding model developments in the last decade.

1,169 citations



Journal ArticleDOI
TL;DR: A complete and up-to-date survey of published inventory literature for the deteriorating (decaying) inventory models and a classification scheme is presented along with suggestions for future research.
Abstract: This paper presents a complete and up-to-date survey of published inventory literature for the deteriorating (decaying) inventory models. More specifically, those papers are addressed that consider the effect of deterioration as a function of the on-hand level of inventory. The basic features, extensions and generalization of various models are discussed. A classification scheme is presented along with suggestions for future research.

768 citations


Journal ArticleDOI
TL;DR: The present literature review encompasses multiple lifestyle factors and places infertility in context for the couple by focusing on both males and females, and aims to identify the roles that lifestyle factors play in determining reproductive status.
Abstract: Approximately 10 to 15% of couples are impacted by infertility. Recently, the pivotal role that lifestyle factors play in the development of infertility has generated a considerable amount of interest. Lifestyle factors are the modifiable habits and ways of life that can greatly influence overall health and well-being, including fertility. Many lifestyle factors such as the age at which to start a family, nutrition, weight, exercise, psychological stress, environmental and occupational exposures, and others can have substantial effects on fertility; lifestyle factors such as cigarette smoking, illicit drug use, and alcohol and caffeine consumption can negatively influence fertility while others such as preventative care may be beneficial. The present literature review encompasses multiple lifestyle factors and places infertility in context for the couple by focusing on both males and females; it aims to identify the roles that lifestyle factors play in determining reproductive status. The growing interest and amount of research in this field have made it evident that lifestyle factors have a significant impact on fertility.

424 citations


Journal ArticleDOI
TL;DR: The present literature will help in knowing the trends of male factor infertility in developing nations like India and to find out in future, various factors that may be responsible for male infertility.
Abstract: Infertility and problems of impaired fecundity have been a concern through ages and is also a significant clinical problem today, which affects 8-12% of couples worldwide. Of all infertility cases, approximately 40-50% is due to "male factor" infertility and as many as 2% of all men will exhibit suboptimal sperm parameters. It may be one or a combination of low sperm concentration, poor sperm motility, or abnormal morphology. The rates of infertility in less industrialized nations are markedly higher and infectious diseases are responsible for a greater proportion of infertility. The present literature will help in knowing the trends of male factor infertility in developing nations like India and to find out in future, various factors that may be responsible for male infertility.

417 citations


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Performance
Metrics

Author's H-index: 15

No. of papers from the Author in previous years
YearPapers
20212
20201
20191
20184
20176
20164