scispace - formally typeset
Search or ask a question
Author

Manisha Pal

Bio: Manisha Pal is an academic researcher from University of Calcutta. The author has contributed to research in topics: Optimal design & Mixture model. The author has an hindex of 15, co-authored 84 publications receiving 861 citations.


Papers
More filters
Journal ArticleDOI
TL;DR: Binary logistic regression analysis revealed that both HBV/A and 1762T/1764A mutations are predictors of chronic liver disease state over asymptomatic carrier state, highlighting the possible influence of HBV genotype shift on the changing scenario ofHBV epidemiology and disease in the population.
Abstract: In a previous study from eastern India, the prevalence of HBV/C has been increasing among the blood donors. In order to analyze whether there has been any shift in HBV genotype distributions in recent years, the HBV genotypes prevalent during the periods 2000–2002 (Group-I; n = 176) and 2007–2009 (Group-II; n = 203) were compared, with special attention to changes in the proportion of HBV/C. The rate of prevalence of the three HBV genotypes (A, C, and D; percent prevalence 19.9/21.6/58.5 in Group-I vs. 31.0/28.6/40.4 in Group-II) underwent significant changes with increases in HBV/A and HBV/C among the HBV carriers (0.002). Among the asymptomatic carriers, the prevalence of these two genotypes (P = 0.021 for HBV/A and P = 0.005 for HBV/C) was significantly high. A notable increase was also observed among the chronic liver disease cases. HBV/A increased significantly among the older age Groups (≥51 years), whereas the increase of HBV/C was significant among the younger age Groups (≤20 years). With the increase of HBV/A and HBV/C, the rates of basal core promoter double mutation (1762T/1764A) also increased considerably. Binary logistic regression analysis revealed that both HBV/A and 1762T/1764A mutations are predictors of chronic liver disease state over asymptomatic carrier state. Thus, this study highlights the possible influence of HBV genotype shift on the changing scenario of HBV epidemiology and disease in the population. J. Med. Virol. 85:1340–1347, 2013. © 2013 Wiley Periodicals, Inc.

16 citations

Journal ArticleDOI
TL;DR: In this paper, a modified maximum-likelihood method and a Bayesian technique have been used to estimate R = P(Y < X), when X and Y are distributed as two independent four-parameter generalized gamma random variables with same location and scale parameters.
Abstract: In this paper we consider estimation of R = P(Y < X), when X and Y are distributed as two independent four-parameter generalized gamma random variables with same location and scale parameters. A modified maximum likelihood method and a Bayesian technique have been used to estimate R on the basis of independent samples. As the Bayes estimator cannot be obtained in a closed form, it has been implemented using importance sampling procedure. A simulation study has also been carried out to compare the two methods.

16 citations

Journal ArticleDOI
TL;DR: In this paper, the deficiency criterion due to Chatterjee and Mandal (1981) has been used as a measure for comparing the performance of competing mixture models, and the problem of estimating the optimum proportion of mixture components is of great practical importance.
Abstract: In a mixture experiment the measured response is assumed to depend only on the relative proportion of ingredients or components present in the mixture. Scheffe (1958, 1963) first systematically considered this problem and introduced different models and designs suitable in such situations. Optimum designs for the estimation of parameters of different mixture models are available in the literature. The problem of estimating the optimum proportion of mixture components is of great practical importance. Pal and Mandal (2006, 2007) attempted to find a solution to this problem by adopting a pseudo-Bayesian approach and using the trace criterion. Subsequently, Pal and Mandal (2008) solved the problem using minimax criterion. In this article, the deficiency criterion due to Chatterjee and Mandal (1981) has been used as a measure for comparing the performance of competing designs.

16 citations

Journal ArticleDOI
TL;DR: The association of types of pre-S mutations with particular HBV genotype and clinical outcome in the study population is highlighted and underscores the link between mutation/deletion in HBV/A andHBV/C.

16 citations

Journal ArticleDOI
01 Sep 2007-Opsearch
TL;DR: In this paper, a deterministic inventory model is developed for deteriorating items with general rate of deterioration and with stock dependent demand when shortages are observed, conditions of permissible delay in payments are also taken into consideration.
Abstract: In this paper a deterministic inventory model is developed for deteriorating items with general rate of deterioration and with stock dependent demand when shortages are observed. Conditions of permissible delay in payments are also taken into consideration. Numerical examples are cited to illustrate the model.

15 citations


Cited by
More filters
Journal ArticleDOI
TL;DR: The motivations, extensions and generalizations of various models in each sub-class have been discussed in brief to bring out pertinent information regarding model developments in the last decade.

1,247 citations

Journal ArticleDOI
TL;DR: A complete and up-to-date survey of published inventory literature for the deteriorating (decaying) inventory models and a classification scheme is presented along with suggestions for future research.
Abstract: This paper presents a complete and up-to-date survey of published inventory literature for the deteriorating (decaying) inventory models. More specifically, those papers are addressed that consider the effect of deterioration as a function of the on-hand level of inventory. The basic features, extensions and generalization of various models are discussed. A classification scheme is presented along with suggestions for future research.

812 citations

Journal ArticleDOI
TL;DR: The present literature will help in knowing the trends of male factor infertility in developing nations like India and to find out in future, various factors that may be responsible for male infertility.
Abstract: Infertility and problems of impaired fecundity have been a concern through ages and is also a significant clinical problem today, which affects 8-12% of couples worldwide. Of all infertility cases, approximately 40-50% is due to "male factor" infertility and as many as 2% of all men will exhibit suboptimal sperm parameters. It may be one or a combination of low sperm concentration, poor sperm motility, or abnormal morphology. The rates of infertility in less industrialized nations are markedly higher and infectious diseases are responsible for a greater proportion of infertility. The present literature will help in knowing the trends of male factor infertility in developing nations like India and to find out in future, various factors that may be responsible for male infertility.

656 citations

Journal ArticleDOI
TL;DR: The present literature review encompasses multiple lifestyle factors and places infertility in context for the couple by focusing on both males and females, and aims to identify the roles that lifestyle factors play in determining reproductive status.
Abstract: Approximately 10 to 15% of couples are impacted by infertility. Recently, the pivotal role that lifestyle factors play in the development of infertility has generated a considerable amount of interest. Lifestyle factors are the modifiable habits and ways of life that can greatly influence overall health and well-being, including fertility. Many lifestyle factors such as the age at which to start a family, nutrition, weight, exercise, psychological stress, environmental and occupational exposures, and others can have substantial effects on fertility; lifestyle factors such as cigarette smoking, illicit drug use, and alcohol and caffeine consumption can negatively influence fertility while others such as preventative care may be beneficial. The present literature review encompasses multiple lifestyle factors and places infertility in context for the couple by focusing on both males and females; it aims to identify the roles that lifestyle factors play in determining reproductive status. The growing interest and amount of research in this field have made it evident that lifestyle factors have a significant impact on fertility.

535 citations