M
Manon Queudeville
Researcher at Boston Children's Hospital
Publications - 31
Citations - 340
Manon Queudeville is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Internal medicine & Leukemia. The author has an hindex of 9, co-authored 23 publications receiving 234 citations. Previous affiliations of Manon Queudeville include University of Ulm & University of Tübingen.
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Journal ArticleDOI
Early Relapse in ALL Is Identified by Time to Leukemia in NOD/SCID Mice and Is Characterized by a Gene Signature Involving Survival Pathways
Lüder Hinrich Meyer,SM Eckhoff,Manon Queudeville,Johann M. Kraus,Marco Giordan,Jana Stursberg,Andrea Zangrando,Elena Vendramini,Anja Möricke,Martin Zimmermann,André Schrauder,Georgia Lahr,Karlheinz Holzmann,Martin Schrappe,Giuseppe Basso,Karsten Stahnke,Hans A. Kestler,Geertruy te Kronnie,Klaus-Michael Debatin +18 more
TL;DR: Investigation of engraftment properties and impact on patient outcome of 50 pediatric acute lymphoblastic leukemia samples transplanted into NOD/SCID mice found short TTL was strongly associated with high risk for early relapse, identifying an independent prognostic factor.
Journal ArticleDOI
Efficacy, safety and feasibility of antifungal prophylaxis with posaconazole tablet in paediatric patients after haematopoietic stem cell transplantation.
Michaela Döring,Karin Melanie Cabanillas Stanchi,Manon Queudeville,Judith Feucht,Franziska Blaeschke,Patrick Schlegel,Tobias Feuchtinger,Peter Lang,Ingo Müller,Rupert Handgretinger,Werner J. Heinz +10 more
TL;DR: The administration of posaconazole tablets was safe, effective and feasible as antifungal prophylaxis in paediatric patients after HSCT and they are effective in preventing invasive fungal infections in children with haemato-oncological malignancies.
Journal ArticleDOI
Blinatumomab in pediatric patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia
Manon Queudeville,Patrick Schlegel,Amadeus T Heinz,Teresa Lenz,Michaela Döring,Ursula Holzer,Ulrike Hartmann,Hermann Kreyenberg,Arend von Stackelberg,Martin Schrappe,Gerhard Zugmaier,Tobias Feuchtinger,Peter Lang,Rupert Handgretinger,Martin Ebinger +14 more
TL;DR: In this article, the authors evaluated the response rates, adverse events, and long-term follow-up of pediatric patients with relapsed/refractory acute lymphoblastic leukemia receiving blinatumomab.
Journal ArticleDOI
Neurotoxic side effects in children with refractory or relapsed T-cell malignancies treated with nelarabine based therapy.
Michaela Kuhlen,Kirsten Bleckmann,Anja Möricke,Martin Schrappe,Simon Vieth,Gabriele Escherich,Annika Bronsema,Annika Vonalt,Manon Queudeville,C. Michel Zwaan,Martin Ebinger,Klaus-Michael Debatin,Thomas Klingebiel,Ewa Koscielniak,Claudia Rossig,Birgit Burkhardt,R Kolb,Cornelia Eckert,Arndt Borkhardt,Arend von Stackelberg,Christiane Chen-Santel +20 more
TL;DR: No differences were observed between mono‐ and combination therapy concerning outcome and neuro‐AE, and the incidence of neuro‐ AE was not associated with concurrent intrathecal therapy or prior central nervous system irradiation.
Journal ArticleDOI
Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia.
M. Schirmer,Livio Trentin,Livio Trentin,Manon Queudeville,Manon Queudeville,Felix Seyfried,Salih Demir,Eugen Tausch,Stephan Stilgenbauer,SM Eckhoff,LH Meyer,Klaus-Michael Debatin +11 more
TL;DR: Importantly, BV6 increased the effectivity of conventional induction therapy including vincristine, dexamethasone and asparaginase leading to prolonged remission induction, suggesting SMAC-mimetics as an important addendum to efficient therapy of pediatric BCP-ALL.