M
Manouchehr Ashrafpour
Researcher at Babol University of Medical Sciences
Publications - 21
Citations - 284
Manouchehr Ashrafpour is an academic researcher from Babol University of Medical Sciences. The author has contributed to research in topics: Kindling model & Hippocampal formation. The author has an hindex of 11, co-authored 21 publications receiving 215 citations.
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Journal ArticleDOI
Curcumin-loaded nanoparticles ameliorate glial activation and improve myelin repair in lyolecithin-induced focal demyelination model of rat corpus callosum.
Reza Naeimi,Fatemeh Safarpour,Mona Hashemian,Hamed Tashakorian,Seyed Raheleh Ahmadian,Manouchehr Ashrafpour,Maryam Ghasemi-Kasman +6 more
TL;DR: Findings indicate that treatment with curcumin-loaded NPs preserve myelinated axons through amelioration of glial activation and inflammation in demyelination context.
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Upregulation of klotho and erythropoietin contributes to the neuroprotection induced by curcumin-loaded nanoparticles in experimental model of chronic epilepsy.
Sahar Rostami Mansoor,Mona Hashemian,Mohsen Khalili-Fomeshi,Manouchehr Ashrafpour,Ali Akbar Moghadamnia,Maryam Ghasemi-Kasman +5 more
TL;DR: The results of this study suggest that downregulation of TNF-α and consequent upregulation of klotho and EPO might contribute to the neuroprotective effect of curcumin-loaded NPs in experimental model of epilepsy.
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Arbutin attenuates behavioral impairment and oxidative stress in an animal model of Parkinson's disease.
Masoumeh Dadgar,Mahdi Pouramir,Zohreh Dastan,Maryam Ghasemi-Kasman,Manouchehr Ashrafpour,Ali Akbar Moghadamnia,Soraya Khafri,Mohsen Pourghasem +7 more
TL;DR: It is suggested that arbutin attenuates the behavioral impairment and oxidative stress in a PD animal model and improves motor functions in an MPTP-induced PD model.
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Piperine restores streptozotocin-induced cognitive impairments: Insights into oxidative balance in cerebrospinal fluid and hippocampus.
Mohsen Khalili-Fomeshi,Mohammad Golparvar Azizi,Mohammad Reza Esmaeili,Mohammad Gol,Sohrab Kazemi,Manouchehr Ashrafpour,Ali Akbar Moghadamnia,Soheila Hosseinzadeh +7 more
TL;DR: The cognitive‐enhancing effect induced by piperine at a relevant dose was simultaneous with CSF and hippocampal malonaldehyde decrement, and the redox balance was established to some extent by maintaining the FRAP levels of CSF near to those of the control.
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Querectin improves myelin repair of optic chiasm in lyolecithin-induced focal demyelination model.
Reza Naeimi,Saeideh Baradaran,Manouchehr Ashrafpour,Ali Akbar Moghadamnia,Maryam Ghasemi-Kasman +4 more
TL;DR: It is indicated that quercetin could remarkably improve the functional recovery of the optic pathway by its protective effects on myelin sheath and attenuation of glial activation.