M
Manu R. Varma
Researcher at University of Michigan
Publications - 17
Citations - 1129
Manu R. Varma is an academic researcher from University of Michigan. The author has contributed to research in topics: Venous thrombosis & Thrombus. The author has an hindex of 13, co-authored 16 publications receiving 1079 citations. Previous affiliations of Manu R. Varma include Harvard University & University of Pittsburgh.
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Journal ArticleDOI
Drug-eluting or bare-metal stents for acute myocardial infarction.
Laura Mauri,Treacy S. Silbaugh,Pallav Garg,Robert E. Wolf,Katya Zelevinsky,Ann Lovett,Manu R. Varma,Zheng Zhou,Sharon-Lise T. Normand +8 more
TL;DR: In patients presenting with acute myocardial infarction, treatment with drug-eluting stents is associated with decreased 2-year mortality rates and a reduction in the need for repeat revascularization procedures as compared with treatment with bare-metal stents.
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Drug-eluting or bare-metal stenting in patients with diabetes mellitus: results from the Massachusetts Data Analysis Center Registry.
Pallav Garg,Sharon-Lise T. Normand,Treacy S. Silbaugh,Robert E. Wolf,Katya Zelevinsky,Ann Lovett,Manu R. Varma,Zheng Zhou,Laura Mauri +8 more
TL;DR: In a real-world diabetic patient population with mandatory reporting and follow-up, drug-eluting stents (DES) were associated with reduced mortality, myocardial infarction, and revascularization rates at long-term follow- up compared with BMS.
Journal ArticleDOI
Vein wall remodeling after deep vein thrombosis involves matrix metalloproteinases and late fibrosis in a mouse model
Kristopher B. Deatrick,Jonathan L. Eliason,Erin Lynch,Andrea J. Moore,Nicholas A. Dewyer,Manu R. Varma,Charles G. Pearce,Gilbert R. Upchurch,Thomas W. Wakefield,Peter K. Henke +9 more
TL;DR: In this article, the expression of proteases and collagen involved in early vein wall remodeling was investigated in early venous thrombosis in the mouse, and the results showed that wound healing after DVT is similar to wound healing and is associated with increased procollagen gene expression and total collagen.
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Neutropenia impairs venous thrombosis resolution in the rat.
Manu R. Varma,Andrea Varga,Brian S. Knipp,Pasu Sukheepod,Gilbert R. Upchurch,Steven L. Kunkel,Thomas W. Wakefield,Peter K. Henke +7 more
TL;DR: Neutropenia impairs DVT resolution by several measures, most likely by altering normal fibrinolytic activity and thrombus collagen turnover.
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Targeted Deletion of CCR2 Impairs Deep Vein Thombosis Resolution in a Mouse Model
Peter K. Henke,Charles G. Pearce,Daria M. Moaveni,Andrea J. Moore,Erin Lynch,Christopher Longo,Manu R. Varma,Nicholas A. Dewyer,K. Barry Deatrick,Gilbert R. Upchurch,Thomas W. Wakefield,Cory M. Hogaboam,Steven L. Kunkel +12 more
TL;DR: It is concluded that an early CCR2-dependent Th1 lymphokine response predominates in normal DVT resolution, mediates this in part by MMP-9 activation, but is not solely dependent on IFN-γ.