M
Marc A. Pfeffer
Researcher at Brigham and Women's Hospital
Publications - 815
Citations - 143710
Marc A. Pfeffer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 166, co-authored 765 publications receiving 133043 citations. Previous affiliations of Marc A. Pfeffer include Partners HealthCare & University of Miami.
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Journal ArticleDOI
Effect of Infarct Artery Patency on Prognosis After Acute Myocardial Infarction
Gervasio A. Lamas,G. C. Flaker,G F Mitchell,S. C. Smith,B. J. Gersh,C. C. Wun,Lemuel A. Moyé,J. L. Rouleau,John D. Rutherford,Marc A. Pfeffer,Eugene Braunwald +10 more
TL;DR: Findings support the need for additional, prospective clinical trials of late reperfusion in MI patients and determine the effect of angiotensin-converting enzyme (ACE) inhibitor therapy on patients with patent as well as occluded infarct arteries.
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Effect of Pravastatin on Rate of Kidney Function Loss in People With or at Risk for Coronary Disease
Marcello Tonelli,Chris Isles,Timothy E. Craven,Andrew Tonkin,Marc A. Pfeffer,James Shepherd,Frank M. Sacks,Curt D. Furberg,Stuart M. Cobbe,John Simes,Malcolm J. West,Chris J. Packard,Gary C. Curhan +12 more
TL;DR: Pravastatin modestly reduced the rate of kidney function loss in people with or at risk for cardiovascular disease, however, the primary indication for the use of statins in peoplewith or at high risk for coronary events remains the reduction in mortality that results from their use.
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Usefulness of right ventricular fractional area change to predict death, heart failure, and stroke following myocardial infarction (from the VALIANT ECHO Study).
Nagesh S. Anavekar,Hicham Skali,Mikhail Bourgoun,Jalal K. Ghali,Lars Køber,Aldo P. Maggioni,John J.V. McMurray,Eric J. Velazquez,Robert M. Califf,Marc A. Pfeffer,Scott D. Solomon +10 more
TL;DR: In this article, the authors found that decreased right ventricular systolic function is a major risk factor for death, sudden death, heart failure, and stroke after myocardial infarction.
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On the restricted mean survival time curve in survival analysis.
Lihui Zhao,Brian Claggett,Lu Tian,Hajime Uno,Marc A. Pfeffer,Scott D. Solomon,Lorenzo Trippa,L. J. Wei +7 more
TL;DR: Inference, for instance, based on simultaneous confidence bands for a single RMST curve and also the difference between two RMST curves are proposed, which is informative for evaluating two groups under an equivalence or noninferiority setting, and quantifies the difference of two groups in a time scale.
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Pumping ability of the hypertrophying left ventricle of the spontaneously hypertensive rat.
TL;DR: In the normotensive animal peak cardiac output per gram of LV remained stable over a wide range of ages and varying left ventricular weights, however, with progressive elevation of arterial pressure in aging SHR (83 weeks), the authors observed severe ventricular hypertrophy.