M
Marc A. Pfeffer
Researcher at Brigham and Women's Hospital
Publications - 815
Citations - 143710
Marc A. Pfeffer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 166, co-authored 765 publications receiving 133043 citations. Previous affiliations of Marc A. Pfeffer include Partners HealthCare & University of Miami.
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Comparison of enalapril versus nifedipine to decrease left ventricular hypertrophy in systemic hypertension (the PRESERVE trial)
TL;DR: The PRESERVE study is designed to provide a definitive test of the ability of enalapril to achieve greater left ventricular (LV) mass reduction than nifedipine GITs by a degree that would be prognostically meaningful on a population basis.
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Prognostic assessment of estimated glomerular filtration rate by the new Chronic Kidney Disease Epidemiology Collaboration equation in comparison with the Modification of Diet in Renal Disease Study equation
TL;DR: The CKD-EPI equation provides more accurate risk stratification than the MDRD Study equation in patients at high risk for CV disease, including identification of increased risk at mildly decreased eGFR.
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Activation of neurohumoral systems in postinfarction left ventricular dysfunction
Jean L. Rouleau,Jacques de Champlain,Marc Klein,Daniel G. Bichet,Lemuel A. Moyé,Milton Packer,Gilles R. Dagenais,Bruce Sussex,J. Malcolm O. Arnold,Francois Sestier,John O. Parker,Patricia McEwan,Victoria Bernstein,T. Edward Cuddy,Gervasio A. Lamas,Stephen S. Gottlieb,John McCans,Claude Nadeau,François Delage,Peggy Hamm,Marc A. Pfeffer +20 more
TL;DR: Although all neurohormones except epinephrine were increased compared with values in age-matched control subjects, plasma norepinephrine values ranged from normal to very high, indicating a wide spectrum of neurohumoral activation.
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Ventricular enlargement and remodeling following acute myocardial infarction: mechanisms and management.
TL;DR: Rational management to prevent severe myocardial ischemia includes restoration of the patency of the occluded vessel and ventricular unloading.
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Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury.
Olaf Eickmeier,Hiroyuki Seki,Oliver Haworth,Jan N. Hilberath,F Gao,Mohib Uddin,Roxanne H. Croze,Troy Carlo,Marc A. Pfeffer,Bruce D. Levy +9 more
TL;DR: Findings indicate that AT-RvD1 displays potent mucosal protection and promotes catabasis after ALI.