M
Marc A. Pfeffer
Researcher at Brigham and Women's Hospital
Publications - 815
Citations - 143710
Marc A. Pfeffer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 166, co-authored 765 publications receiving 133043 citations. Previous affiliations of Marc A. Pfeffer include Partners HealthCare & University of Miami.
Papers
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Journal ArticleDOI
Association of QRS duration and outcomes after myocardial infarction: the VALIANT trial.
Lakshminarayan Yerra,Nagesh S. Anavekar,Hicham Skali,Steve Zelenkofske,Eric J. Velazquez,John J.V. McMurray,Marc A. Pfeffer,Scott D. Solomon +7 more
TL;DR: Prolonged QRS duration, even within the normal range, is associated with larger ventricular volumes, reduced systolic function, and an increased risk for development of HF, SD, and CV death after MI but appears to be a marker, rather than an independent predictor, for increased risk.
Cardiac hypertrophy and performance of Dahl hypertensive rats on graded salt diets. Hypertension
TL;DR: The relationship between arterial pressure and left ventricular functional capacity and LV mass during the natural development of cardiac hypertrophy was assessed in Dahl-resistant (R) and -sensitive (S) hypertensive rats maintained on three dietary NaCl regimens (0.4, 4.0, and 8.0%) from 5 until 20 weeks of age as mentioned in this paper.
Journal ArticleDOI
Predictors of stroke in high-risk patients after acute myocardial infarction: insights from the VALIANT trial
Uchechukwu Sampson,Marc A. Pfeffer,John J.V. McMurray,Yuliya Lokhnygina,Harvey D. White,Scott D. Solomon +5 more
TL;DR: Among high-risk patients presenting with MI but without initial neurological symptoms, the risk of stroke 6 weeks thereafter is 0.94% (95% CI 0.78-1.09).
Journal ArticleDOI
Hemodynamics of spontaneously hypertensive rats. I. Effects of pressure elevation.
Marc A. Pfeffer,E. D. Frohlich +1 more
Journal ArticleDOI
Patients with prior coronary artery bypass grafting have a poor outcome after myocardial infarction: an analysis of the VALsartan in acute myocardial iNfarcTion trial (VALIANT).
Colin Berry,Karen S. Pieper,Harvey D. White,Scott D. Solomon,Frans Van de Werf,Eric J. Velazquez,Aldo P. Maggioni,Robert M. Califf,Marc A. Pfeffer,John J.V. McMurray +9 more
TL;DR: Patients with prior CABG had a worse clinical profile and experienced more fatal and non-fatal outcomes in the VALIANT trial, and greater recognition is necessary for these high-risk patients including optimization of evidence-based secondary preventive therapy.