M
Marc Gwadz
Researcher at National Institutes of Health
Publications - 15
Citations - 14364
Marc Gwadz is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Conserved Domain Database & Entrez. The author has an hindex of 10, co-authored 12 publications receiving 11728 citations.
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Journal ArticleDOI
CDD: a Conserved Domain Database for the functional annotation of proteins
Aron Marchler-Bauer,Shennan Lu,John B. Anderson,Farideh Chitsaz,Myra K. Derbyshire,Carol DeWeese-Scott,Jessica H. Fong,Lewis Y. Geer,Renata C. Geer,Noreen R. Gonzales,Marc Gwadz,David I. Hurwitz,John D. Jackson,Zhaoxi Ke,Christopher J. Lanczycki,Fu-Ping Lu,Gabriele H. Marchler,Mikhail Mullokandov,Marina V. Omelchenko,Cynthia L. Robertson,James S. Song,Narmada Thanki,Roxanne A. Yamashita,Dachuan Zhang,Naigong Zhang,Chanjuan Zheng,Stephen H. Bryant +26 more
TL;DR: NCBI’s Conserved Domain Database (CDD) is a resource for the annotation of protein sequences with the location of conserved domain footprints, and functional sites inferred from these footprints.
Journal ArticleDOI
CDD: NCBI's conserved domain database
Aron Marchler-Bauer,Myra K. Derbyshire,Noreen R. Gonzales,Shennan Lu,Farideh Chitsaz,Lewis Y. Geer,Renata C. Geer,Jane He,Marc Gwadz,David I. Hurwitz,Christopher J. Lanczycki,Fu Lu,Gabriele H. Marchler,James S. Song,Narmada Thanki,Zhouxi Wang,Roxanne A. Yamashita,Dachuan Zhang,Chanjuan Zheng,Stephen H. Bryant +19 more
TL;DR: NCBI's CDD, the Conserved Domain Database, enters its 15th year as a public resource for the annotation of proteins with the location of conserved domain footprints and aims at increasing coverage and providing finer-grained classifications of common protein domains.
Journal ArticleDOI
CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.
Aron Marchler-Bauer,Yu Bo,Lianyi Han,Jane He,Christopher J. Lanczycki,Shennan Lu,Farideh Chitsaz,Myra K. Derbyshire,Renata C. Geer,Noreen R. Gonzales,Marc Gwadz,David I. Hurwitz,Fu Lu,Gabriele H. Marchler,James S. Song,Narmada Thanki,Zhouxi Wang,Roxanne A. Yamashita,Dachuan Zhang,Chanjuan Zheng,Lewis Y. Geer,Stephen H. Bryant +21 more
TL;DR: NCBI's Conserved Domain Database (CDD) aims at annotating biomolecular sequences with the location of evolutionarily conserved protein domain footprints, and functional sites inferred from such footprints.
Journal ArticleDOI
CDD/SPARCLE: the conserved domain database in 2020
Shennan Lu,Jiyao Wang,Farideh Chitsaz,Myra K. Derbyshire,Renata C. Geer,Noreen R. Gonzales,Marc Gwadz,David I. Hurwitz,Gabriele H. Marchler,James S. Song,Narmada Thanki,Roxanne A. Yamashita,Mingzhang Yang,Dachuan Zhang,Chanjuan Zheng,Christopher J. Lanczycki,Aron Marchler-Bauer +16 more
TL;DR: As NLM's Conserved Domain Database (CDD) enters its 20th year of operations as a publicly available resource, curation staff continues to develop hierarchical classifications of widely distributed protein domain families, and to record conserved sites associated with molecular function, so that they can be mapped onto user queries in support of hypothesis-driven biomolecular research.
Journal ArticleDOI
CDD: a Conserved Domain Database for protein classification
Aron Marchler-Bauer,John B. Anderson,Praveen F. Cherukuri,Carol DeWeese-Scott,Lewis Y. Geer,Marc Gwadz,Siqian He,David I. Hurwitz,John D. Jackson,Zhaoxi Ke,Christopher J. Lanczycki,Cynthia A. Liebert,Chunlei Liu,Fu Lu,Gabriele H. Marchler,Mikhail Mullokandov,Benjamin A. Shoemaker,Vahan Simonyan,James S. Song,Paul A. Thiessen,Roxanne A. Yamashita,Jodie J. Yin,Dachuan Zhang,Stephen H. Bryant +23 more
TL;DR: The progress of the curation effort and associated improvements in the functionality of the CDD information retrieval system are reported on.