M
Marc K. Rosenblum
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 304
Citations - 22559
Marc K. Rosenblum is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Glioma & Cancer. The author has an hindex of 73, co-authored 284 publications receiving 19890 citations. Previous affiliations of Marc K. Rosenblum include Mount Sinai Hospital & University of Pennsylvania.
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Journal ArticleDOI
The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex
Richard W. Price,Bruce J. Brew,John J. Sidtis,Marc K. Rosenblum,Adrienne C. Scheck,Paul D. Cleary +5 more
TL;DR: Within the context of the permissive effect of immunosuppression, genetic changes in HIV-1 may underlie the neuropathological heterogeneity of the AIDS dementia complex and its relatively independent course in relation to the systemic manifestations of AIDS noted in some patients.
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An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
Dan Rohle,Janeta Popovici-Muller,Nicolaos Palaskas,Sevin Turcan,Christian Grommes,Carl Campos,Jennifer Tsoi,Owen Clark,Barbara Oldrini,Evangelia Komisopoulou,Kaiko Kunii,Alicia Pedraza,Stefanie Schalm,Lee Silverman,Alexandra Miller,Fang Wang,Hua Yang,Yue Chen,Andrew Kernytsky,Marc K. Rosenblum,Wei Liu,Scott A. Biller,Shinsan M. Su,Cameron Brennan,Timothy A. Chan,Thomas G. Graeber,Katharine E. Yen,Ingo K. Mellinghoff,Ingo K. Mellinghoff +28 more
TL;DR: The recent discovery of mutations in metabolic enzymes has rekindled interest in harnessing the altered metabolism of cancer cells for cancer therapy, and isocitrate dehydrogenase 1 (IDH1), which is mutated in multiple human cancers, is examined.
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Anti-Hu--associated paraneoplastic encephalomyelitis/sensory neuronopathy. A clinical study of 71 patients.
TL;DR: Patients with rapidly developing sensory neuropathy or symptoms of encephalomyelitis should be studied for the presence of the anti-Hu antibody; if the antibody is found, the possibility of small-cell lung cancer should be investigated.
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Paraneoplastic cerebellar degeneration.: I.A clinical analysis of 55 anti‐Yo antibody‐positive patients
TL;DR: The presence of the anti-Yo antibody in patients with cerebellar symptoms warrants an aggressive approach to diagnosis and treatment of the underlying cancer, as many are curable at the time neurologic symptoms develop.
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International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading
David N. Louis,Arie Perry,Peter C. Burger,David W. Ellison,Guido Reifenberger,Andreas von Deimling,Kenneth Aldape,Daniel J. Brat,V. Peter Collins,Charles G. Eberhart,Dominique Figarella-Branger,Gregory N. Fuller,Felice Giangaspero,Caterina Giannini,Cynthia Hawkins,Paul Kleihues,Andrey Korshunov,Johan M. Kros,M. Beatriz S. Lopes,Ho Keung Ng,Hiroko Ohgaki,Werner Paulus,Torsten Pietsch,Marc K. Rosenblum,Elisabeth J. Rushing,Figen Soylemezoglu,Otmar D. Wiestler,Pieter Wesseling +27 more
TL;DR: The present “white paper” catalogs the recommendations of the meeting, at which a consensus was reached that incorporation of molecular information into the next WHO classification of central nervous system tumors should follow a set of provided “ISN‐Haarlem” guidelines.