Marc Klein

TL;DR: In patients with asymptomatic left ventricular dysfunction after myocardial infarction, long-term administration of captopril was associated with an improvement in survival and reduced morbidity and mortality due to major cardiovascular events.

TL;DR: This study demonstrates the linkage between attenuation of left ventricular enlargement by captopril after infarction and improved clinical outcome and two-dimensional echocardiography provides important and independent prognostic information in patients afterinfarction.

TL;DR: The threshold for the admission of patients to a coronary care unit or for the use of invasive diagnostic and therapeutic interventions in the early and late periods after an infarction is higher in Canada than in the United States, which is associated with a higher frequency of activity-limiting angina.

TL;DR: Only plasma renin activity and aldosterone, atrial natriuretic peptide and arginine vasopressin were independent predictors of the combined end points of cardiovascular mortality, development of severe heart failure or recurrent myocardial infarction.

TL;DR: The beneficial effects of beta-blocker use at the time of hospital discharge in patients with asymptomatic left ventricular dysfunction after myocardial infarction appear to be additive to those of captopril and other interventions known to improve prognosis.