M
Marcel A. Behr
Researcher at McGill University
Publications - 292
Citations - 17326
Marcel A. Behr is an academic researcher from McGill University. The author has contributed to research in topics: Tuberculosis & Mycobacterium tuberculosis. The author has an hindex of 64, co-authored 273 publications receiving 15586 citations. Previous affiliations of Marcel A. Behr include Montreal Chest Institute & Stanford University.
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Journal ArticleDOI
Comparative Genomics of BCG Vaccines by Whole-Genome DNA Microarray
Marcel A. Behr,Michael A Wilson,W. P. Gill,Hugh Salamon,Gary K. Schoolnik,Sangeeta Rane,Peter M. Small +6 more
TL;DR: In this article, the differences between M. tuberculosis, M. bovis, and Bacille Calmette-Guerin (BCG) vaccines were studied by performing comparative hybridization experiments on a DNA microarray.
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Transmission of Mycobacterium tuberculosis from patients smear-negative for acid-fast bacilli
Marcel A. Behr,S. A. Warren,Hugh Salamon,Philip C. Hopewell,A. Ponce de Leon,Charles L. Daley,Peter M. Small +6 more
TL;DR: In San Francisco, the acid-fast-bacilli smear identifies the most infectious patients, but patients with smear-negative culture-positive tuberculosis appear responsible for about 17% of tuberculosis transmission.
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Deletion of RD1 from Mycobacterium tuberculosis Mimics Bacille Calmette-Guérin Attenuation
Kaeryn N. Lewis,Reiling Liao,Kristi M. Guinn,Mark J. Hickey,Sherilyn Smith,Marcel A. Behr,David R. Sherman +6 more
TL;DR: It was concluded that genes within or controlled by RD1 are essential for MTB virulence and that loss of RD1 was important in BCG attenuation.
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Genome plasticity of BCG and impact on vaccine efficacy.
Roland Brosch,Stephen V. Gordon,Thierry Garnier,Karin Eiglmeier,Wafa Frigui,Philippe Valenti,Sandrine Dos Santos,Stephanie Duthoy,Céline Lacroix,Carmen Garcia-Pelayo,Jacqueline Inwald,Paul Golby,Javier Nunez Garcia,R. Glyn Hewinson,Marcel A. Behr,Michael A. Quail,Carol Churcher,Bart Barrell,Julian Parkhill,Stewart T. Cole +19 more
TL;DR: The combined findings suggest that early BCG vaccines may even be superior to the later ones that are more widely used, and that further amplification of the DU2 region is ongoing, even within vaccine preparations used to immunize humans.
Journal ArticleDOI
The BCG World Atlas: A Database of Global BCG Vaccination Policies and Practices
Alice Zwerling,Marcel A. Behr,Marcel A. Behr,Aman Verma,Timothy F. Brewer,Dick Menzies,Dick Menzies,Dick Menzies,Madhukar Pai,Madhukar Pai +9 more
TL;DR: The BCG World Atlas is introduced, an open access, user friendly Web site for TB clinicians to discern global BCG vaccination policies and practices and improve the care of their patients.