M
Márcio Machado Costa
Researcher at Universidade de Passo Fundo
Publications - 85
Citations - 1048
Márcio Machado Costa is an academic researcher from Universidade de Passo Fundo. The author has contributed to research in topics: Trypanosoma evansi & Parasitemia. The author has an hindex of 17, co-authored 79 publications receiving 950 citations. Previous affiliations of Márcio Machado Costa include Universidade Federal de Santa Maria.
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Journal ArticleDOI
Cytokines in rats experimentally infected with Trypanosoma evansi.
Francine C. Paim,Marta M.M.F. Duarte,Márcio Machado Costa,Aleksandro Schafer da Silva,Patrícia Wolkmer,Cássia B. da Silva,Carlos Breno Paim,Raqueli T. França,Cinthia M. Mazzanti,Silvia Gonzalez Monteiro,Alexandre Krause,Sonia Terezinha dos Anjos Lopes +11 more
TL;DR: It is concluded that the infection caused by T. evansi causes an increase in the pro-inflammatory cytokines and a synergism among IL-1, TNF-α and IFN-γ contributing to the development of anemia.
Journal ArticleDOI
Experimental infection with Rangelia vitalii in dogs: acute phase, parasitemia, biological cycle, clinical-pathological aspects and treatment.
Aleksandro Schafer da Silva,Raqueli T. França,Márcio Machado Costa,Carlos Breno Paim,Francine C. Paim,Guilherme Lopes Dornelles,João Fabio Soares,Marcelo Bahia Labruna,Cinthia M. Mazzanti,Silvia Gonzalez Monteiro,Sonia Terezinha dos Anjos Lopes +10 more
TL;DR: The parasitemia, biological cycles and clinical-pathological findings in dogs experimentally infected with R. vitalii in the acute phase of disease were evaluated, and a therapeutic protocol based on the diminazene aceturate was tested, which showed a curative efficacy of 100% in cleaning R. Vitalii from blood of infected dogs.
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Identification of vector-borne pathogens in dogs and cats from Southern Brazil
J. Malheiros,Márcio Machado Costa,R.B. do Amaral,K.C.M. de Sousa,Marcos Rogério André,Rosangela Zacarias Machado,Maria Isabel Botelho Vieira +6 more
TL;DR: This is the first time that B. vogeli detected among cats in Southern Brazil, and findings compatible with rangeliosis, such as anemia, thrombocytopenia, external bleeding, and anorexia are found.
Journal ArticleDOI
Rangelia vitalli in dogs in southern Brazil
Raqueli T. França,Aleksandro Schafer da Silva,Francine C. Paim,Márcio Machado Costa,João Fabio Soares,Cinthia M. Mazzanti,Sonia Terezinha dos Anjos Lopes +6 more
TL;DR: Important hematological findings observed in these cases were severe anemia and thrombocytopenia and therapeutic protocol based on prednisone, doxycycline, and dipropionate which had great curative efficacy to rangeliosis.
Journal ArticleDOI
Resposta eritropoética de ratos em diferentes graus de parasitemia por Trypanosoma evansi
Patrícia Wolkmer,Aleksandro Schafer da Silva,Juliana Felipetto Cargnelutti,Márcio Machado Costa,Carolina Kist Traesel,Sonia Terezinha dos Anjos Lopes,Silvia Gonzalez Monteiro +6 more
TL;DR: O Trypanosoma evansi e um protozoario hemoflagelado que causa, em varias especies, uma doenca caracterizada por altos niveis de parasitemia, com rapido desenvolvimento de anemia desenvolvem uma anemia aguda, com um aumento compensatorio na atividade hematopoetica.