M
Marco A. van den Berg
Researcher at DSM
Publications - 74
Citations - 4082
Marco A. van den Berg is an academic researcher from DSM. The author has contributed to research in topics: Penicillium chrysogenum & Gene. The author has an hindex of 28, co-authored 71 publications receiving 3655 citations. Previous affiliations of Marco A. van den Berg include Delft University of Technology & Leiden University.
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Journal ArticleDOI
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
Herman Jan Pel,Johannes H. de Winde,Johannes H. de Winde,David B. Archer,Paul S. Dyer,Gerald Hofmann,Peter J. Schaap,Geoffrey Turner,Ronald P. de Vries,Richard Albang,Kaj Albermann,Mikael Rørdam Andersen,Jannick Dyrløv Bendtsen,Jacques A.E. Benen,Marco A. van den Berg,Stefaan Breestraat,Mark X. Caddick,Roland Contreras,Michael Cornell,Pedro M. Coutinho,Etienne Danchin,Alfons J. M. Debets,Peter J. T. Dekker,Piet W.M. van Dijck,Alard Van Dijk,Lubbert Dijkhuizen,Arnold J. M. Driessen,Christophe d'Enfert,Steven Geysens,Coenie Goosen,Gert S.P. Groot,Piet W. J. de Groot,Thomas Guillemette,Bernard Henrissat,Marga Herweijer,Johannes Petrus Theodorus Wilhelmus Van Den Hombergh,Cees A. M. J. J. van den Hondel,René T. J. M. van der Heijden,Rachel M. van der Kaaij,Frans M. Klis,Harrie J. Kools,Christian P. Kubicek,Patricia Ann van Kuyk,Jürgen Lauber,Xin Lu,Marc J. E. C. van der Maarel,Rogier Meulenberg,Hildegard Henna Menke,Martin Mortimer,Jens Nielsen,Stephen G. Oliver,Maurien M.A. Olsthoorn,K. Pal,K. Pal,Noël Nicolaas Maria Elisabeth Van Peij,Arthur F. J. Ram,Ursula Rinas,Johannes Andries Roubos,Cornelis Maria Jacobus Sagt,Monika Schmoll,Jibin Sun,David W. Ussery,János Varga,Wouter Vervecken,Peter J.J. Van De Vondervoort,Holger Wedler,Han A. B. Wösten,An-Ping Zeng,Albert J. J. van Ooyen,Jaap Visser,Hein Stam +70 more
TL;DR: The filamentous fungus Aspergillus niger is widely exploited by the fermentation industry for the production of enzymes and organic acids, particularly citric acid, and the sequenced genome revealed a large number of major facilitator superfamily transporters and fungal zinc binuclear cluster transcription factors.
Journal ArticleDOI
Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum
Marco A. van den Berg,Richard Albang,Kaj Albermann,Jonathan H. Badger,Jean-Marc Daran,Arnold J. M. Driessen,Carlos García-Estrada,Natalie D. Fedorova,Diana M. Harris,Wilbert H. M. Heijne,Vinita Joardar,Jan A.K.W. Kiel,Andriy Kovalchuk,Juan F. Martín,William C. Nierman,William C. Nierman,Jeroen G. Nijland,Jack T. Pronk,Johannes Andries Roubos,Ida J. van der Klei,Noël Nicolaas Maria Elisabeth Van Peij,Marten Veenhuis,Hans von Döhren,Christian Wagner,Jennifer R. Wortman,Roel A. L. Bovenberg +25 more
TL;DR: Genes predicted to encode transporters were strongly overrepresented among the genes transcriptionally upregulated under conditions that stimulate penicillinG production, illustrating potential for future genomics-driven metabolic engineering.
Journal ArticleDOI
The Two Acetyl-coenzyme A Synthetases of Saccharomyces cerevisiae Differ with Respect to Kinetic Properties and Transcriptional Regulation
Marco A. van den Berg,Marco A. van den Berg,Patricia de Jong-Gubbels,Christine J. Kortland,Christine J. Kortland,Johannes P. van Dijken,Jack T. Pronk,H. Yde Steensma,H. Yde Steensma +8 more
TL;DR: Characterization of enzyme activities in cell-free extracts from strains expressing either of the ACS1 and ACS2 genes revealed differences in the catalytic properties of the two enzymes, indicating that ACS2 (in)directly is involved in the transcriptional regulation of ACS1.
Journal ArticleDOI
The sequence of a 1.8-Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways
Marnix H. Medema,Axel Christoph Trefzer,Andriy Kovalchuk,Marco A. van den Berg,Ulrike Müller,Wilbert H. M. Heijne,Liang Wu,Mohammad Tauqeer Alam,Catherine M. Ronning,William C. Nierman,Roel A. L. Bovenberg,Rainer Breitling,Rainer Breitling,Eriko Takano +13 more
TL;DR: Phylogenetic analysis indicates that heavy traffic of genetic information between Streptomyces plasmids and chromosomes may facilitate the rapid evolution of secondary metabolite repertoires in these bacteria.
Journal ArticleDOI
ACS2, a Saccharomyces Cerevisiae Gene Encoding Acetyl‐Coenzyme A Synthetase, Essential for Growth on Glucose
TL;DR: A second gene encoding acetyl-coenzyme A synthetase, which is called ACS2, is cloned, which indicates that ACS2 is essential for growth on glucose in batch cultures, and the acs1-acs2 double mutant was not viable.