Marcus Ferrone

TL;DR: This first-in-man imaging study evaluated the safety and feasibility of hyperpolarized [1-13C]pyruvate as an agent for noninvasively characterizing alterations in tumor metabolism for patients with prostate cancer and showed elevated levels of lactate, alanine, and bicarbonate in regions of biopsy-proven cancer.

TL;DR: The purpose of this study was to develop and implement experimental strategies for using [1‐13C]pyruvate to probe in vivo metabolism for patients with brain tumors and other neurological diseases.

TL;DR: The delivery of sufficient enzyme concentrations into the duodenal lumen simultaneously with meals can reduce nutrient malabsorption, improve the symptoms of steatorrhea, and in some cases alleviate the pain associated with chronic pancreatitis.

TL;DR: To determine the risk of PICC-related BSI in hospitalized patients, a prospectively studied cohort study using data from 2 randomized trials assessing the efficacy of chlorhexidine-impregnated sponge dressing and chlor hexidine for cutaneous antisepsis was conducted.

TL;DR: The molecular imaging approach applied to investigate differences in perfusion and metabolism between low- and high-grade tumors in the transgenic adenocarcinoma of mouse prostate (TRAMP) transgenic mouse model of prostate cancer could be translated to investigate these imaging biomarkers for their diagnostic and prognostic power in future prostate cancer clinical trials.