M
Marcus Flather
Researcher at University of East Anglia
Publications - 331
Citations - 50627
Marcus Flather is an academic researcher from University of East Anglia. The author has contributed to research in topics: Myocardial infarction & Coronary artery disease. The author has an hindex of 83, co-authored 307 publications receiving 43997 citations. Previous affiliations of Marcus Flather include McMaster University & Leeds General Infirmary.
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Journal ArticleDOI
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
Paul M. Ridker,Brendan M. Everett,Tom Thuren,Jean G. MacFadyen,William Chang,Christie M. Ballantyne,Francisco H. Fonseca,Jose C. Nicolau,Wolfgang Koenig,Stefan D. Anker,John J.P. Kastelein,Jan H. Cornel,Prem Pais,Daniel Pella,Jacques Genest,Renata Cifkova,Alberto J. Lorenzatti,Tamás Forster,Zhanna Kobalava,Luminita Vida-Simiti,Marcus Flather,Hiroaki Shimokawa,Hisao Ogawa,Mikael Dellborg,Paulo Roberto Ferreira Rossi,Roland P.T. Troquay,Peter Libby,Robert J. Glynn +27 more
TL;DR: Antiinflammatory therapy targeting the interleukin‐1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid‐level lowering.
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Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events
Deepak L. Bhatt,Keith A.A. Fox,Werner Hacke,Peter B. Berger,Henry R. Black,William E. Boden,Patrice Cacoub,Eric A. Cohen,Mark A. Creager,J. Donald Easton,Marcus Flather,Steven M. Haffner,Christian W. Hamm,Graeme J. Hankey,S. Claiborne Johnston,Koon Hou Mak,Jean-Louis Mas,Gilles Montalescot,Thomas A. Pearson,P. Gabriel Steg,Steven R. Steinhubl,Michael A. Weber,Danielle M. Brennan,Liz Fabry-Ribaudo,Joan E. Booth,Eric J. Topol +25 more
TL;DR: In this article, the authors compared the effect of clopidogrel and low-dose aspirin on the rate of myocardial infarction, stroke, or death from cardiovascular causes.
Journal ArticleDOI
Predictors of hospital mortality in the global registry of acute coronary events.
Christopher B. Granger,Robert J. Goldberg,Omar H. Dabbous,Karen S. Pieper,Kim A. Eagle,Christopher P. Cannon,Frans Van de Werf,Alvaro Avezum,Shaun G. Goodman,Marcus Flather,Keith A.A. Fox +10 more
TL;DR: Across the entire spectrum of ACS and in general clinical practice, this model provides excellent ability to assess the risk for death and can be used as a simple nomogram to estimate risk in individual patients.
Journal ArticleDOI
ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group.
Rory Collins,Richard Peto,Marcus Flather,Sarah Parish,Peter Sleight,M Conway,A Pipilis,Colin Baigent,D Barnett,J P Boissel,Andrzej Budaj,John A. Cairns,L Ceremuzynski,Alexander T. Cohen,G Debacker,Rafael Diaz,F Dienstl,P Dove,MariaGrazia Franzosi,Genoni M,D Halon,J Heikkila,Charles H. Hennekens,J Horgan,D Hunt,R Kala,N Karatzas,Anthony C Keech,Matyas Keltai,J Kjekshus,M Kornitzer,R Koster,P Landless,P Lechleitner,Alain Leizorovicz,B Lewis,L Lundkvist,Stephen MacMahon,Aldo P. Maggioni,R Malacrida,T Meyer,Tiziano Moccetti,D Ocallaghan,Ernesto Paolasso,Leopoldo S. Piegas,A Reikvam,Paul M. Ridker,T Ryan,R Schroder,R Seabragomes,J Sousa,G Tognoni,Alexander G.G. Turpie,Valentin,J Varigos,H White,L Wilhelmsen,K Woods,Salim Yusuf,A Piombo,L Guzman,D Montenegro,G Irusta,R Schneider,C Cuneo,B Chamorro,G Espinosa,M Moreno,M Rios,Richard Doll,Keith A.A. Fox,D Julian,P Meier,E Sandoya,J Perez +74 more
TL;DR: In this paper, the authors compared the effects of three different treatment regimens (captopril, controlled-release mononitrate, and intravenous magnesium sulphate) for acute myocardial infarction.
Journal ArticleDOI
ACC/AHA/ESC Guidelines for the Management of Patients With Atrial Fibrillation: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation) Developed in Collaboration With the North American Society of Pacing and Electrophysiology
Valentin Fuster,Lars Rydén,Richard W. Asinger,David S. Cannom,Harry J.G.M. Crijns,Robert L. Frye,Jonathan L. Halperin,G. Neal Kay,Werner Klein,Samuel Lévy,Robert L. McNamara,Eric N. Prystowsky,L. Samuel Wann,D. George Wyse,Raymond J. Gibbons,Elliott M. Antman,Joseph S. Alpert,David P. Faxon,Gabriel Gregoratos,Loren F. Hiratzka,Alice K. Jacobs,Richard O. Russell,Sidney C. Smith,Angeles Alonso-Garcia,Carina Blomström-Lundqvist,Guy De Backer,Marcus Flather,Jaromír Hradec,Ali Oto,A. Parkhomenko,Sigmund Silber,Adam Torbicki +31 more
TL;DR: New guidelines for management of supraventricular tachyarrhythmia characterized by uncoordinated atrial activation with consequent deterioration of atrial mechanical function are published.