M
Maria C. Costanzo
Researcher at Stanford University
Publications - 42
Citations - 12713
Maria C. Costanzo is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 29, co-authored 38 publications receiving 11422 citations. Previous affiliations of Maria C. Costanzo include Princeton University & Wellcome Trust.
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Journal ArticleDOI
The Gene Ontology (GO) database and informatics resource.
Midori A. Harris,Jennifer I. Clark,Ireland A,Jane Lomax,Michael Ashburner,Michael Ashburner,R. Foulger,R. Foulger,Karen Eilbeck,Karen Eilbeck,Suzanna E. Lewis,Suzanna E. Lewis,B. Marshall,B. Marshall,Christopher J. Mungall,Christopher J. Mungall,J. Richter,J. Richter,Gerald M. Rubin,Gerald M. Rubin,Judith A. Blake,Carol J. Bult,Dolan M,Drabkin H,Janan T. Eppig,Hill Dp,L. Ni,Ringwald M,Rama Balakrishnan,Rama Balakrishnan,J. M. Cherry,J. M. Cherry,Karen R. Christie,Karen R. Christie,Maria C. Costanzo,Maria C. Costanzo,Selina S. Dwight,Selina S. Dwight,Stacia R. Engel,Stacia R. Engel,Dianna G. Fisk,Dianna G. Fisk,Jodi E. Hirschman,Jodi E. Hirschman,Eurie L. Hong,Eurie L. Hong,Robert S. Nash,Robert S. Nash,Anand Sethuraman,Anand Sethuraman,Chandra L. Theesfeld,Chandra L. Theesfeld,David Botstein,David Botstein,Kara Dolinski,Kara Dolinski,Becket Feierbach,Becket Feierbach,Tanya Z. Berardini,Tanya Z. Berardini,S. Mundodi,S. Mundodi,Seung Y. Rhee,Seung Y. Rhee,Rolf Apweiler,Daniel Barrell,Camon E,E. Dimmer,Lee,Rex L. Chisholm,Pascale Gaudet,Pascale Gaudet,Warren A. Kibbe,Warren A. Kibbe,Ranjana Kishore,Ranjana Kishore,Erich M. Schwarz,Erich M. Schwarz,Paul W. Sternberg,Paul W. Sternberg,M. Gwinn,Hannick L,Wortman J,Matthew Berriman,Matthew Berriman,Wood,Wood,de la Cruz N,de la Cruz N,Peter J. Tonellato,Peter J. Tonellato,Pankaj Jaiswal,Pankaj Jaiswal,Seigfried T,Seigfried T,White R,White R +96 more
TL;DR: The Gene Ontology (GO) project as discussed by the authors provides structured, controlled vocabularies and classifications that cover several domains of molecular and cellular biology and are freely available for community use in the annotation of genes, gene products and sequences.
Journal ArticleDOI
Saccharomyces Genome Database: the genomics resource of budding yeast
J. Michael Cherry,Eurie L. Hong,Craig Amundsen,Rama Balakrishnan,Gail Binkley,Esther T. Chan,Karen R. Christie,Maria C. Costanzo,Selina S. Dwight,Stacia R. Engel,Dianna G. Fisk,Jodi E. Hirschman,Benjamin C. Hitz,Kalpana Karra,Cynthia J. Krieger,Stuart R. Miyasato,Robert S. Nash,Julie Park,Marek S. Skrzypek,Matt Simison,Shuai Weng,Edith D. Wong +21 more
TL;DR: The Saccharomyces Genome Database is an encyclopedia of the yeast genome, its chromosomal features, their functions and interactions, and public access to these data is provided to researchers and educators via web pages designed for optimal ease of use.
Journal ArticleDOI
Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
Geraldine Butler,Matthew D. Rasmussen,Michael F. Lin,Michael F. Lin,Manuel A. S. Santos,Sharadha Sakthikumar,Carol A. Munro,Esther Rheinbay,Esther Rheinbay,Manfred Grabherr,Anja Forche,Jennifer L. Reedy,Ino Agrafioti,Martha B. Arnaud,Steven Bates,Alistair J. P. Brown,Sascha Brunke,Maria C. Costanzo,David A. Fitzpatrick,Piet W. J. de Groot,David Harris,Lois L. Hoyer,Bernhard Hube,Frans M. Klis,Chinnappa D. Kodira,Nicola Lennard,Mary E. Logue,Ronny Martin,Aaron M. Neiman,Elissavet Nikolaou,Michael A. Quail,Janet Quinn,Maria C. Santos,Florian F. Schmitzberger,Gavin Sherlock,Prachi Shah,Kevin A. T. Silverstein,Marek S. Skrzypek,David R. Soll,Rodney Staggs,Ian Stansfield,Michael P. H. Stumpf,Peter E. Sudbery,Thyagarajan Srikantha,Qiandong Zeng,Judith Berman,Matthew Berriman,Joseph Heitman,Neil A. R. Gow,Michael C. Lorenz,Bruce W. Birren,Manolis Kellis,Manolis Kellis,Christina A. Cuomo +53 more
TL;DR: There are significant expansions of cell wall, secreted and transporter gene families in pathogenic species, suggesting adaptations associated with virulence in Candida albicans species.
Journal ArticleDOI
Big data: The future of biocuration.
Doug Howe,Maria C. Costanzo,Petra Fey,Takashi Gojobori,Linda Hannick,Winston Hide,Winston Hide,David P. Hill,Renate Kania,Mary L. Schaeffer,Mary L. Schaeffer,Susan E. St. Pierre,Simon N. Twigger,Owen White,Seung Y. Rhee +14 more
TL;DR: To thrive, the field that links biologists and their data urgently needs structure, recognition and support.
Journal ArticleDOI
The Gene Ontology project in 2008
Midori A. Harris,Jennifer I. Deegan,Amelia Ireland,Jane Lomax,Michael Ashburner,Susan Tweedie,Seth Carbon,Suzanna E. Lewis,Christopher J. Mungall,John Day Richter,Karen Eilbeck,Judith A. Blake,Carol J. Bult,Alexander D. Diehl,Mary E. Dolan,Harold J. Drabkin,Janan T. Eppig,David P. Hill,Ni Li,Martin Ringwald,Rama Balakrishnan,Gail Binkley,J. Michael Cherry,Karen R. Christie,Maria C. Costanzo,Qing Dong,Stacia R. Engel,Dianna G. Fisk,Jodi E. Hirschman,Benjamin C. Hitz,Eurie L. Hong,Cynthia J. Krieger,Stuart R. Miyasato,Robert S. Nash,Julie Park,Marek S. Skrzypek,Shuai Weng,Edith D. Wong,Kathy K. Zhu,David Botstein,Kara Dolinski,Michael S. Livstone,Rose Oughtred,Tanya Z. Berardini,Li Donghui,Seung Y. Rhee,Rolf Apweiler,Daniel Barrell,Evelyn Camon,Emily Dimmer,Rachael P. Huntley,Nicola Mulder,Varsha K. Khodiyar,Ruth C. Lovering,Sue Povey,Rex L. Chisholm,Petra Fey,Pascale Gaudet,Warren A. Kibbe,Ranjana Kishore,Erich M. Schwarz,Paul W. Sternberg,Kimberly Van Auken,Michelle G. Giglio,Linda Hannick,Jennifer R. Wortman,Martin Aslett,Matthew Berriman,Valerie Wood,Howard J. Jacob,Stan Laulederkind,Victoria Petri,Mary Shimoyama,Jennifer L. Smith,Simon N. Twigger,Pankaj Jaiswal,Trent E. Seigfried,Doug Howe,Monte Westerfield,Candace Collmer,Trudy Torto Alalibo,Erika Feltrin,Giorgio Valle,Susan Bromberg,Shane C. Burgess,Fiona M. McCarthy +85 more
TL;DR: The GO Consortium has launched a focused effort to provide comprehensive and detailed annotation of orthologous genes across a number of ‘reference’ genomes, including human and several key model organisms.