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Maria José Soares Mendes-Giannini

Researcher at Sao Paulo State University

Publications -  167
Citations -  5434

Maria José Soares Mendes-Giannini is an academic researcher from Sao Paulo State University. The author has contributed to research in topics: Paracoccidioides brasiliensis & Paracoccidioidomycosis. The author has an hindex of 41, co-authored 162 publications receiving 4643 citations. Previous affiliations of Maria José Soares Mendes-Giannini include University of São Paulo & Instituto Adolfo Lutz.

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Journal ArticleDOI

Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis.

Liliana Scorzoni, +8 more
- 23 Jan 2017 - 
TL;DR: Different approaches to preventing and treating fungal diseases are described in this review, with a focus on the resistance mechanisms of fungi, with the goal of developing efficient strategies to overcoming and preventing resistance as well as new advances in antifungal therapy.
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Glyceraldehyde-3-Phosphate Dehydrogenase of Paracoccidioides brasiliensis Is a Cell Surface Protein Involved in Fungal Adhesion to Extracellular Matrix Proteins and Interaction with Cells

Mônica Santiago Barbosa, +7 more
- 01 Jan 2006 - 
TL;DR: The characterization of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) of P. brasiliensis as an adhesin is reported, which can be related to fungus adhesion and invasion and could be involved in mediating binding of fungal cells to fibronectin, type I collagen, and laminin thus contributing to the adhesion of the microorganism to host tissues and to the dissemination of infection.
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Imbalance of IL-2, IFN-gamma and IL-10 secretion in the immunosuppression associated with human paracoccidioidomycosis.

Gil Benard, +5 more
- 01 Feb 2001 - 
TL;DR: The results suggest that the imbalance in cytokine production of patients with PCM plays a role in the gp43-hyporesponsiveness and the marked (non-protective) antibody production of these patients.
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Fungal Biofilms and Polymicrobial Diseases

Caroline Barcelos Costa-Orlandi, +11 more
- 10 May 2017 - 
TL;DR: Several in vitro techniques have been developed to study fungal biofilms, from colorimetric methods to omics approaches that aim to identify new therapeutic strategies by developing new compounds to combat these microbial communities as well as new diagnostic tools to identify these complex formations in vivo.
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Antifungal efficacy during Candida krusei infection in non-conventional models correlates with the yeast in vitro susceptibility profile.

Liliana Scorzoni, +9 more
- 28 Mar 2013 - 
TL;DR: This work demonstrates that non mammalian models are useful tools to investigate in vivo antifungal efficacy and virulence of C. krusei and uses the lepidopteran Galleria mellonella and the nematode Caenorhabditis elegans as models to assess antifundal efficacy during infection by C.Krusei.