M
Maria L. Allende
Researcher at National Institutes of Health
Publications - 37
Citations - 6392
Maria L. Allende is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Sphingosine & Signal transduction. The author has an hindex of 25, co-authored 36 publications receiving 5862 citations.
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Journal ArticleDOI
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
Mehrdad Matloubian,Charles G. Lo,Guy Cinamon,Matthew J. Lesneski,Ying Xu,Volker Brinkmann,Maria L. Allende,Richard L. Proia,Jason G. Cyster +8 more
TL;DR: It is established that S1P1 is essential for lymphocyte recirculation and that it regulates egress from both thymus and peripheral lymphoid organs.
Journal ArticleDOI
Mice Deficient in Sphingosine Kinase 1 Are Rendered Lymphopenic by FTY720
Maria L. Allende,Teiji Sasaki,Hiromichi Kawai,Ana Olivera,Yide Mi,Gerhild van Echten-Deckert,Richard Hajdu,Mark Rosenbach,Carol Ann Keohane,Suzanne M. Mandala,Sarah Spiegel,Richard L. Proia +11 more
TL;DR: The results with these Sphk1 null mice reveal that some key physiologic processes that require S1P receptor signaling, such as vascular development and proper lymphocyte distribution, can occur in the absence of SPHK1.
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Expression of the Sphingosine 1-Phosphate Receptor, S1P1, on T-cells Controls Thymic Emigration
TL;DR: The results indicated that the expression of the S1P1 receptor on T-cells controls their exit from the thymus and entry into the blood and, thus, has a central role in regulating the numbers of peripheral T- cells.
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The Sphingosine-1-phosphate Receptors S1P1, S1P2, and S1P3 Function Coordinately during Embryonic Angiogenesis
Mari Kono,Yide Mi,Yujing Liu,Teiji Sasaki,Maria L. Allende,Yun-Ping Wu,Tadashi Yamashita,Richard L. Proia +7 more
TL;DR: The results indicate that the S 1P1, S1P2 and S1p3 receptors have redundant or cooperative functions for the development of a stable and mature vascular system during embryonic development.
Journal ArticleDOI
G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation
TL;DR: Using the Cre/loxP system, the S1P1 gene solely in ECs is disrupted and the phenotype of the conditional mutant embryos mimicked the one obtained in the embryos globally deficient in S1p1.