Maria S. Andersen

TL;DR: Advances in high-throughput RNA sequencing and circRNA-specific computational tools have driven the development of state-of-the-art approaches for their identification, and novel approaches to functional characterization are emerging.

TL;DR: A map of circRNA expression in B-cell malignancies based on high-throughput RNA sequencing and an enzyme-free digital counting methodology, which has the potential to become a new gold standard for circRNA quantification are provided.

TL;DR: It is demonstrated that CRISPR/RfxCas13d (CasRx)-mediated circRNA depletion is, for the circRNAs studied, more efficient than Argonaute 2-dependent short hairpin RNA (agoshRNA)-mediated depletion and with fewer off-target effects on the linear host RNAs.

TL;DR: The aim of this project was to examine and evaluate the patients’ experience of nurse-driven diagnostic process and develop a “smart phrase” for the documentation platform in the interdisciplinary working group to ensure continuity in the conversation with the patient.

TL;DR: In this article , the authors show that circRNA levels increased substantially over the course of differentiation of human embryonic stem cells into rostral and caudal neural progenitor cells (NPCs), including three of the most abundant circRNAs, ciRS-7, circRMST, and circFAT3.