M
Maria T. Vassileva
Researcher at Foundation for the National Institutes of Health
Publications - 17
Citations - 3450
Maria T. Vassileva is an academic researcher from Foundation for the National Institutes of Health. The author has contributed to research in topics: Sarcopenia & SUMO protein. The author has an hindex of 15, co-authored 17 publications receiving 2783 citations. Previous affiliations of Maria T. Vassileva include Johns Hopkins University.
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Journal ArticleDOI
The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates
Stephanie A. Studenski,Katherine W. Peters,Dawn E. Alley,Peggy M. Cawthon,Robert R. McLean,Tamara B. Harris,Luigi Ferrucci,Jack M. Guralnik,Maren S. Fragala,Anne M. Kenny,Douglas P. Kiel,Stephen B. Kritchevsky,Michelle Shardell,Thuy Tien L. Dam,Maria T. Vassileva +14 more
TL;DR: Based on the analyses presented in this series, the final recommended cutpoints for weakness are grip strength <26kg for men and <16kg for women, and for low lean mass, appendicular lean mass adjusted for body mass index <0.789 forMen and women.
Journal ArticleDOI
Grip Strength Cutpoints for the Identification of Clinically Relevant Weakness
Dawn E. Alley,Michelle Shardell,Katherine W. Peters,Robert R. McLean,Thuy Tien L. Dam,Anne M. Kenny,Maren S. Fragala,Maren S. Fragala,Tamara B. Harris,Douglas P. Kiel,Jack M. Guralnik,Luigi Ferrucci,Stephen B. Kritchevsky,Stephanie A. Studenski,Maria T. Vassileva,Peggy M. Cawthon +15 more
TL;DR: Cutpoints for weakness derived from this large, diverse sample of older adults may be useful to identify populations who may benefit from interventions to improve muscle strength and function.
Journal ArticleDOI
Criteria for Clinically Relevant Weakness and Low Lean Mass and Their Longitudinal Association With Incident Mobility Impairment and Mortality: The Foundation for the National Institutes of Health (FNIH) Sarcopenia Project
Robert R. McLean,Michelle Shardell,Dawn E. Alley,Peggy M. Cawthon,Maren S. Fragala,Maren S. Fragala,Tamara B. Harris,Anne M. Kenny,Katherine W. Peters,Luigi Ferrucci,Jack M. Guralnik,Stephen B. Kritchevsky,Douglas P. Kiel,Maria T. Vassileva,Qian Li Xue,Subashan Perera,Stephanie A. Studenski,Thuy Tien L. Dam +17 more
TL;DR: Findings support the cut-points for low grip strength and low ALM-to-BMI ratio as candidate criteria for clinically relevant weakness and low lean mass and further validation in other populations and for alternate relevant outcomes is needed.
Journal ArticleDOI
An Evidence-Based Comparison of Operational Criteria for the Presence of Sarcopenia
Thuy Tien L. Dam,Katherine W. Peters,Maren S. Fragala,Peggy M. Cawthon,Tamara B. Harris,Robert R. McLean,Michelle Shardell,Dawn E. Alley,Anne M. Kenny,Luigi Ferrucci,Jack M. Guralnik,Douglas P. Kiel,Steve B. Kritchevsky,Maria T. Vassileva,Stephanie A. Studenski +14 more
TL;DR: The FNIH criteria result in a more conservative operational definition of sarcopenia, and the prevalence was lower compared with other proposed criteria, including the International Working Group and the European Working Group for Sarcopenia in Older Persons.
Journal ArticleDOI
Cutpoints for Low Appendicular Lean Mass That Identify Older Adults With Clinically Significant Weakness
Peggy M. Cawthon,Katherine W. Peters,Michelle Shardell,Robert R. McLean,Thuy Tien L. Dam,Anne M. Kenny,Maren S. Fragala,Maren S. Fragala,Tamara B. Harris,Douglas P. Kiel,Jack M. Guralnik,Luigi Ferrucci,Stephen B. Kritchevsky,Maria T. Vassileva,Stephanie A. Studenski,Dawn E. Alley +15 more
TL;DR: ALM cutpoints derived from a large, diverse sample of older adults identified lean mass thresholds below which older adults had a higher likelihood of weakness.