M
Mariana Laranjo
Researcher at University of Coimbra
Publications - 5
Citations - 56
Mariana Laranjo is an academic researcher from University of Coimbra. The author has contributed to research in topics: Medicine & Immunology. The author has an hindex of 2, co-authored 2 publications receiving 31 citations.
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Journal ArticleDOI
Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice
Mohamed Edfawy,Joana R. Guedes,Marta I Pereira,Mariana Laranjo,Mário Jorge da Silva Carvalho,Xian Gao,Xian Gao,Xian Gao,Pedro A. Ferreira,Gladys L. Caldeira,Lara O. Franco,Dongqing Wang,Ana L. Cardoso,Guoping Feng,Guoping Feng,Guoping Feng,Ana Luísa Carvalho,João Peça +17 more
TL;DR: It is shown that Gprasp2 deletion leads to ASD-like behaviour in mice and alterations in synaptic communication, and a possible mechanism by which this gene is linked to neurodevelopmental diseases is suggested.
Journal ArticleDOI
A biocompatible redox MRI probe based on a Mn( ii )/Mn( iii ) porphyrin
Sara M. A. Pinto,Mário J. F. Calvete,Mariana Emilia Ghica,Sergio Soler,Iluminada Gallardo,Agnès Pallier,Mariana Laranjo,Ana M. Cardoso,M. Margarida C. A. Castro,Christopher M.A. Brett,Mariette M. Pereira,Éva Tóth,Carlos F. G. C. Geraldes +12 more
TL;DR: Water soluble fluorinated Mn-porphyrin derivative Mn-3 acts as an ascorbate specific turn-on MRI probe, which in turn can be re-oxidized by oxygen, and the relaxivity increase from the oxidized to the reduced form is considerably improved at medium frequencies.
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Attenuation of Autism-like Behaviors by an Anthocyanin-Rich Extract from Portuguese Blueberries via Microbiota–Gut–Brain Axis Modulation in a Valproic Acid Mouse Model
Diana Serra,Joana Henriques,F. J. Sousa,Mariana Laranjo,Rosa Resende,Marisa Ferreira-Marques,Victor de Freitas,Gabriela Silva,João Peça,Teresa C.P. Dinis,Leonor M. Almeida +10 more
TL;DR: It is suggested that anthocyanins extracted from Portuguese blueberries could constitute an effective strategy to ameliorate typical autistic behaviors through modulation of the microbiota–gut–brain axis.
Journal ArticleDOI
Brain Gain – Discovering Neurosciences: A digital education outreach project for higher education students
TL;DR: Brain Gain this article is a series of open-access and digital education outreach events targeting higher education students, including online talks, pitch challenges, a podcast and a mentorship program, which has reached over 1000 students and their initiatives have been rated as excellent by participants and scientists.
Journal ArticleDOI
IL-4 Shapes Microglia-Dependent Pruning of the Cerebellum During Postnatal Development
Joana R. Guedes,Pedro A. Ferreira,Jéssica Costa,Mariana Laranjo,Tiago Reis,Ana L. Cardoso,Carolina Lebre,Maria Casquinha,Marcos Gomes,Viktoriya Shkatova,M Pereira,Nuno Beltrão,Christina F. Vogelaar,Ana Luísa Carvalho,Frauke Zipp,João Miguel Peça +15 more