Author
Mariana Mitewa
Other affiliations: Bulgarian Academy of Sciences, University of Zagreb
Bio: Mariana Mitewa is an academic researcher from Sofia University. The author has contributed to research in topics: Ligand & Denticity. The author has an hindex of 18, co-authored 138 publications receiving 1395 citations. Previous affiliations of Mariana Mitewa include Bulgarian Academy of Sciences & University of Zagreb.
Topics: Ligand, Denticity, Monensin, Electron paramagnetic resonance, 15-Crown-5
Papers published on a yearly basis
Papers
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TL;DR: In this paper, the synthesis, characterization and cytotoxic activity of gold(III) complexes containing N1-acylacetamidrazones was reported and the complexes have general formula AuX3(L), where X = Cl, Br and L = amidrazone ligands.
Abstract: The synthesis, characterization and cytotoxic activity of gold(III) complexes containing N1-acylacetamidrazones is reported. The complexes have general formula AuX3(L), where X = Cl, Br and L = amidrazone ligands. In all cases, the complexes appear to be monomeric and square planar.
11 citations
TL;DR: It is reported that a newly identified metabolite of quetiapine, N-desalkylquetiAPine, can be used as an indicative marker of quetsiapines-intake in urine using common GC-MS screening procedure.
Abstract: Quetiapine fumarate (Seroquel®) is an atypical antipsychotic dibenzothiazepine derivative. Due to its extensive hepatic metabolism and low level of unchanged excretion (< 1%) the routine toxicological drug-screening analyses of urine often leads to false negative results. In the present study, we report that a newly identified metabolite of quetiapine, N-desalkylquetiapine, can be used as an indicative marker of quetiapine-intake in urine using common GC-MS screening procedure. The structure of the mentioned metabolite was solved from the mass-spectrum obtained and the quetiapine presence was proved by consequent HPLC plasma analysis.
11 citations
Journal Article•
TL;DR: The crystal structures of four cycloalkanespiro-4'-imidazolidine-2',5'-dithiones, namely cyclopentanepiro, 4-IMIDZolidine 2, 5-dithione, cycloheptane-2,4]-nonane and cyclooctane ring assume both boat-chair and boat-boat conformations.
Abstract: The crystal structures of four cycloalkanespiro-4'-imidazolidine-2',5'-dithiones, namely cyclopentanespiro-4'-imidazolidine-2',5'-dithione {systematic name: 1,3-diazaspiro[4.4]-nonane-2,4-dithione}, C 7 H 10 N 2 S 2 , cyclohexanespiro-4'-imidazolidine-2',5'-dithione (systematic name: 1,3-diazaspiro[4.5]-decane-2,4-dithione), C 8 H 12 N 2 S 2 , cycloheptanespiro-4'-imidazolidine-2',5'-dithione (systematic name: 1,3-diazaspiro[4.6]-undecane-2,4-dithione), C 9 H 14 N 2 S 2 , and cyclooctanespiro-4'-imidazolidine-2',5'-dithione (systematic name: 1,3-diazaspiro[4.7]dodecane-2,4-dithione), C 10 H 16 N 2 S 2 , have been determined. The three-dimensional packing in all of the structures is based on closely similar chains, in which hydantoin moieties are linked through N-H···S hydrogen bonding. The size of the cycloalkane moiety influences the degree of its deformation. In the cyclooctane compound, the cyclooctane ring assumes both boat-chair and boat-boat conformations.
10 citations
TL;DR: In this paper, the Cu(II) complexes of three hydrazides of aspartic and glutamic acids have been obtained and studied using electronic IR and EPR spectra, DTA, magnetic susceptibility measurements, extraction, ion exchange and elemental analysis data.
10 citations
TL;DR: In this paper, the structure and coordination modes of paramagnetic complexes with biuret (BiuH2) were studied using magnetochemical and spectroscopic (EPR, IR, ESCA) methods.
Abstract: New monomeric Pd(III) and dimeric (Pd(III)-Pd(II)) paramagnetic complexes with biuret (BiuH2) were synthesized and their structures and coordination modes studied using magnetochemical and spectroscopic (EPR, IR, ESCA) methods. For the monomeric species a metal to ligand ratio 1:2 was found and for the dimeric one it was 2:3. A distorted rhombic structure was suggested for the [Pd(III)(Biu)2]− species. For the dimeric complex it was accepted that one of the biuret molecules is serving as bridging ligand coordinated via both NH-groups to one of the palladium ions and via both C=O groups to the other. A distorted rhombic structure is suggested for each of the palladium ions. Referee I: W. A. Donaldson Referee II: N. M. Kostic
10 citations
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1,365 citations
TL;DR: The spectrum of gold complexes described as antiproliferative compounds comprises a broad variety of different species including many phosphine complexes as well as gold in different oxidation states.
700 citations
TL;DR: This contribution aims at an elucidation of some of the underlying principles of heavy and transition metal ion-enhanced emission by analyzing various systems published by other researchers as well as own work.
494 citations
TL;DR: Guanidines have attracted increasing attention as electronically and sterically flexible ligands as mentioned in this paper, exhibiting a variety of coordination modes and a range of donor properties leading to compatibility with a remarkably wide range of metal ions from all parts of the periodic table.
476 citations