Author
Mariana Mitewa
Other affiliations: Bulgarian Academy of Sciences, University of Zagreb
Bio: Mariana Mitewa is an academic researcher from Sofia University. The author has contributed to research in topics: Ligand & Denticity. The author has an hindex of 18, co-authored 138 publications receiving 1395 citations. Previous affiliations of Mariana Mitewa include Bulgarian Academy of Sciences & University of Zagreb.
Topics: Ligand, Denticity, Monensin, Electron paramagnetic resonance, 15-Crown-5
Papers published on a yearly basis
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TL;DR: The crystal structures of four cycloalkanespiro-4′-imidazolidine-2′,5′-dithiones, namely cyclo-pentane spiro- 4′-IMidazolicine- 2′, 5′- dithione, have been determined and the three-dimensional packing is based on closely similar chains, in which hydantoin moieties are linked through N—H⋯S hydrogen bonding.
Abstract: The crystal structures of four cycloalkanespiro-4′-imidazolidine-2′,5′-dithiones, namely cyclopentanespiro-4′-imidazolidine-2′,5′-dithione {systematic name: 1,3-diazaspiro[4.4]nonane-2,4-dithione}, C7H10N2S2, cyclohexanespiro-4′-imidazolidine-2′,5′-dithione {systematic name: 1,3-diazaspiro[4.5]decane-2,4-dithione}, C8H12N2S2, cycloheptanespiro-4′-imidazolidine-2′,5′-dithione {systematic name: 1,3-diazaspiro[4.6]undecane-2,4-dithione}, C9H14N2S2, and cyclooctanespiro-4′-imidazolidine-2′,5′-dithione {systematic name: 1,3-diazaspiro[4.7]dodecane-2,4-dithione}, C10H16N2S2, have been determined. The three-dimensional packing in all of the structures is based on closely similar chains, in which hydantoin moieties are linked through N—H⋯S hydrogen bonding. The size of the cycloalkane moiety influences the degree of its deformation. In the cyclooctane compound, the cyclooctane ring assumes both boat–chair and boat–boat conformations.
10 citations
TL;DR: A modified isocratic reverse phase high-performance liquid-chromatographic (RP-HPLC) method for phospholipase (PLA) activity assay was successfully applied to snake venom PLA2 activity assay using natural and synthetic substrates.
Abstract: A modified isocratic reverse phase high-performance liquid-chromatographic (RP-HPLC) method for phospholipase (PLA) activity assay is developed. Natural lecithins and synthetic phospholipids are used as substrates, and released fatty acids are analyzed after single-phase derivatization (with p-bromophenacyl bromide) at low temperature. The procedure allows simultaneous determination of the total and specific phospholipase activity. This method was successfully applied to snake venom PLA2 activity assay using natural (soybean and egg yolk lecithins) and synthetic (dipalmytoylphosphatydylcholine) substrates for quantitative determination of the enzyme activity.
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1,365 citations
TL;DR: The spectrum of gold complexes described as antiproliferative compounds comprises a broad variety of different species including many phosphine complexes as well as gold in different oxidation states.
700 citations
TL;DR: This contribution aims at an elucidation of some of the underlying principles of heavy and transition metal ion-enhanced emission by analyzing various systems published by other researchers as well as own work.
494 citations
TL;DR: Guanidines have attracted increasing attention as electronically and sterically flexible ligands as mentioned in this paper, exhibiting a variety of coordination modes and a range of donor properties leading to compatibility with a remarkably wide range of metal ions from all parts of the periodic table.
476 citations