M
Marie-Paule Kieny
Researcher at World Health Organization
Publications - 88
Citations - 11194
Marie-Paule Kieny is an academic researcher from World Health Organization. The author has contributed to research in topics: Public health & Global health. The author has an hindex of 35, co-authored 85 publications receiving 8105 citations. Previous affiliations of Marie-Paule Kieny include French Institute of Health and Medical Research.
Papers
More filters
Journal ArticleDOI
Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis.
Evelina Tacconelli,Elena Carrara,Alessia Savoldi,Stéphan Juergen Harbarth,Marc Mendelson,Dominique L Monnet,Céline Pulcini,Gunnar Kahlmeter,Jan Kluytmans,Yehuda Carmeli,Marc Ouellette,Kevin Outterson,Jean B. Patel,Marco Cavaleri,Edward Cox,Christopher R. Houchens,M Lindsay Grayson,Paul Hansen,Nalini Singh,Ursula Theuretzbacher,Nicola Magrini,Aaron O. Aboderin,Seif Al-Abri,Nordiah Awang Jalil,Nur Benzonana,Sanjay Bhattacharya,Adrian Brink,Francesco Robert Burkert,Otto Cars,Giuseppe Cornaglia,Oliver J. Dyar,Alexander W. Friedrich,Ana Cristina Gales,Sumanth Gandra,Christian G. Giske,Debra A. Goff,Herman Goossens,Thomas Gottlieb,Manuel Guzman Blanco,Waleria Hryniewicz,Deepthi Kattula,Timothy Jinks,Souha S. Kanj,Lawrence Kerr,Marie-Paule Kieny,Yang Soo Kim,Roman S. Kozlov,Jaime Labarca,Ramanan Laxminarayan,Karin Leder,Leonard Leibovici,Gabriel Levy-Hara,Jasper Littman,Surbhi Malhotra-Kumar,Vikas Manchanda,Lorenzo Moja,Babacar Ndoye,Angelo Pan,David L. Paterson,Mical Paul,Haibo Qiu,Pilar Ramon-Pardo,Jesús Rodríguez-Baño,Maurizio Sanguinetti,Sharmila Sengupta,Mike Sharland,Massinissa Si-Mehand,Lynn L. Silver,Wonkeung Song,Martin Steinbakk,Jens Thomsen,Guy E. Thwaites,Jos W. M. van der Meer,Nguyen Van Kinh,Silvio Vega,Maria Virginia Villegas,Agnes Wechsler-Fördös,Heiman F. L. Wertheim,Evelyn Wesangula,Neil Woodford,Fidan O Yilmaz,Anna Zorzet +81 more
TL;DR: Future development strategies should focus on antibiotics that are active against multidrug-resistant tuberculosis and Gram-negative bacteria, and include antibiotic-resistant bacteria responsible for community-acquired infections.
Journal ArticleDOI
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.
Hongchao Pan,Richard Peto,Ana-Maria Henao-Restrepo,Marie-Pierre Preziosi,Vasee Sathiyamoorthy,Quarraisha Abdool Karim,Marissa M. Alejandria,César Hernández García,Marie-Paule Kieny,Reza Malekzadeh,Srinivas Murthy,K. Srinath Reddy,Mirta Roses Periago,Pierre Abi Hanna,Florence Ader,Abdullah M. Al-Bader,Almonther Alhasawi,Emma Allum,Athari Alotaibi,Carlos A Alvarez-Moreno,Sheila Appadoo,Abdullah Asiri,Pål Aukrust,Andreas Barratt-Due,Samir Bellani,Mattia Branca,Heike B. C. Cappel-Porter,Nery Cerrato,Ting S. Chow,Najada Como,Joseph A. Eustace,Patricia J. Garcia,Sheela Godbole,Eduardo Gotuzzo,Laimonas Griskevicius,Rasha Hamra,Mariam Hassan,Mohamed Hassany,David Hutton,Irmansyah Irmansyah,Ligita Jancoriene,Jana Kirwan,Suresh Kumar,Peter Lennon,Gustavo Lopardo,Patrick Lydon,Nicola Magrini,Teresa Maguire,Suzana Manevska,Oriol Manuel,Sibylle McGinty,Marco T. Medina,María L. Mesa Rubio,Maria C. Miranda-Montoya,Jeremy Nel,Estevão Portela Nunes,Markus Perola,Antonio Portolés,Menaldi R. Rasmin,Aun Raza,Helen Rees,Paula P. S. Reges,Chris A Rogers,Kolawole Salami,Marina I. Salvadori,Narvina Sinani,Jonathan A C Sterne,Milena Stevanovikj,Evelina Tacconelli,Kari A.O. Tikkinen,Sven Trelle,Hala Zaid,John-Arne Røttingen,Soumya Swaminathan +73 more
TL;DR: These remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19, as indicated by overall mortality, initiation of ventilation, and duration of hospital stay.
Journal ArticleDOI
Expression of rabies virus glycoprotein from a recombinant vaccinia virus
Marie-Paule Kieny,Richard Lathe,Robert Drillien,Danièle Spehner,S. Skory,D. Schmitt,T. Wiktor,Hilary Koprowski,J P Lecocq +8 more
TL;DR: This work altered the rabies glycoprotein cDNA by site-directed mutagenesis and removed the poly(dG) tail, aligned the modified cDNA with an early VV promoter sequence inserted within a cloned copy of the vaccinia thymidine kinase gene and transfected this plasmid into VV-infected cells to produce a novel rabies vaccine.
Journal ArticleDOI
Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene
Tadeusz J. Wiktor,R I Macfarlan,K J Reagan,Bernhard Dietzschold,P J Curtis,William H. Wunner,Marie-Paule Kieny,Richard Lathe,J P Lecocq,M Mackett +9 more
TL;DR: V-RGpro8 virus was highly effective in priming mice to generate a secondary rabies virus-specific cytotoxic T-lymphocyte response following culture of lymphocytes with either ERA or PM strains of rabiesirus.
Journal ArticleDOI
Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
Selidji T Agnandji,Angela Huttner,Madeleine E Zinser,Patricia Njuguna,Christine Dahlke,José Francisco Fernandes,Sabine Yerly,Julie-Anne Dayer,Verena Kraehling,Rahel Kasonta,A.A. Adegnika,Marcus Altfeld,Floriane Auderset,Emmanuel B. Bache,Nadine Biedenkopf,Saskia Borregaard,Jessica S Brosnahan,Rebekah Burrow,Christophe Combescure,Jules Alexandre Desmeules,Markus Eickmann,Sarah Katharina Fehling,Axel Finckh,Ana Rita Gonçalves,Martin P. Grobusch,Jay W. Hooper,Alen Jambrecina,Anita Lumeka Kabwende,Gürkan Kaya,Domtila Kimani,Bertrand Lell,Barbara Lemaître,Ansgar W. Lohse,Marguerite Massinga-Loembe,Alain Matthey,Benjamin Mordmüller,Anne Nolting,Caroline Ogwang,Michael Ramharter,Jonas Schmidt-Chanasit,Stefan Schmiedel,Peter Silvera,Felix R. Stahl,Henry M. Staines,Thomas Strecker,Hans Stubbe,Benjamin Tsofa,Sherif R. Zaki,Patricia E. Fast,Vasee S. Moorthy,Laurent Kaiser,Sanjeev Krishna,Stephan Becker,Marie-Paule Kieny,Philip Bejon,Peter G. Kremsner,Marylyn M. Addo,Claire-Anne Siegrist +57 more
TL;DR: RVSV-ZEBOV was reactogenic but immunogenic after a single dose and warrants further evaluation for safety and efficacy, and glycoprotein-binding antibody titers were sustained through 180 days in all participants.